Percutaneous Cryoablation of Lung Cancer in High Risk Patients

수술 고위험군 폐암 환자에서의 냉동절제술

  • Lee, Sung-Ho (Department of Thoracic and Cardiovascular Surgery, Anam Hospital, College of Medicine, Korea University) ;
  • Chung, Jae-Ho (Department of Thoracic and Cardiovascular Surgery, Anam Hospital, College of Medicine, Korea University) ;
  • Jo, Sung-Beom (Department of Radiology, College of Medicine, Korea University Anam Hospital) ;
  • Ham, Soo-Youn (Department of Radiology, College of Medicine, Korea University Anam Hospital) ;
  • Son, Ho-Sung (Department of Thoracic and Cardiovascular Surgery, Anam Hospital, College of Medicine, Korea University) ;
  • Kim, Kwang-Taik (Department of Thoracic and Cardiovascular Surgery, Anam Hospital, College of Medicine, Korea University)
  • 이성호 (고려대학교 의과대학 안암병원 흉부외과) ;
  • 정재호 (고려대학교 의과대학 안암병원 흉부외과) ;
  • 조성범 (고려대학교 의과대학 안암병원 영상진단의학과) ;
  • 함수연 (고려대학교 의과대학 안암병원 영상진단의학과) ;
  • 손호성 (고려대학교 의과대학 안암병원 흉부외과) ;
  • 김광택 (고려대학교 의과대학 안암병원 흉부외과)
  • Published : 2006.12.05

Abstract

Surgical resection is the most effective treatment in operable lung cancers. However, less invasive local treatments are being applicated to the patients having high surgical risk due to their poor general condition. Cryosurgery is known to be highly effective and safe in the treatment of liver and prostate cancers and it is also being applicated in the treatment of lung cancers, especially with the excision of tracheal mass and lung parenchymal cancers. In our hospital, we have tried a less Invasive method, the cryotherapy, to a patient who had a newly developed lung cancer at his right lower lobe after he had been treated with right upper lobe resection and left upper lobe resection due to bilateral lung cancels. After the treatment, he is being followed up at our out patient department for 2 years. Here, we present the method and result that have been applicated in this case.

절제 가능한 폐암에서 수술 절제가 가장 효과적인 치료이나 환자의 전신 상태가 불량하여 수술의 위험이 높은 경우 저침습적인 국소 치료방법을 적용한다. 냉동수술요법은 간, 전립선 암의 치료에서 우수한 암치료 효과와 안전성이 있는 치료 방법으로 폐암의 치료에서도 기관지 암종의 제거에 사용되며 폐실질의 종양에도 적용되고 있다. 본원에서는 양측폐에 각각 발생한 폐암으로 두 차례의 우상엽 및 좌상엽 폐절제 수술을 받고 치료 중에 남은 폐의 우하엽에 발생한 폐암으로 내원한 환자에게 저침습 수기로 냉동 치료를 실시하였고 2년간 추적 관찰하였다. 본 증례에서 적용한 냉동 치료의 방법과 결과를 보고한다.

Keywords

References

  1. Gage AA, Baust J. Mechanism of tissue injury in cryosurgery. Cryobiology 1998;37:171-86 https://doi.org/10.1006/cryo.1998.2115
  2. Veth R, Schreuder B, Beem H, Pruszczynski M, Rooy J. Cryosurgery in aggressive, and low-grade malignant bone tumours. Lancet Oncol 2005;6:25-3 https://doi.org/10.1016/S1470-2045(05)70023-1
  3. Maiwand MO. The role of cryosurgery in palliation of tracheo- bronchial carcinoma. Eur J Cardiothorac Surg 1999;15:764-8 https://doi.org/10.1016/S1010-7940(99)00121-9
  4. Maiwand MO, Asimakopoulos G. Cryosurgery for lung cancer: clinical results and technical aspects. Technol Cancer Res Treat 2004;3:143-50 https://doi.org/10.1177/153303460400300207
  5. Maiwand MO, Glynne-Jones R, Chamber J, et al. Direct cryosurgery for inoperable metastatic disease of the lung. Ann Thorac Surg 2006;81:718-21 https://doi.org/10.1016/j.athoracsur.2004.11.018
  6. Wang HW, Zhang YQ, Luo J, et al. Percutaneous lung cancer cryotherapy guided by computer tomography. Zhonghua Jie He He Hu Xi Za Zhi 2004;27:311-4