The Korean Journal of Applied Statistics (응용통계연구)

The Korean Statistical Society (한국통계학회)
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Modified Product-Limit Estimator via Period Analysis

기간분석에 따른 수정된 누적한계 추정량

  • Kim, Jin-Heum (Department of Applied Statistics, University of Suwon) ;
  • Ahn, Yoon-Ok (Department of Preventive Medicine, Seoul National University College of Medicine)
  • 김진흠 (수원대학교 자연과학대학 통계정보학과) ;
  • 안윤옥 (서울대학교 의과대학 예방의학교실)
  • Published : 2006.11.30
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Abstract

Long-term survival rates are the most commonly used outcome measures for patients with cancer. However, traditional long-term survival statistics, which are derived by cohort analysis or complete analysis, essentially reflect the survival expectations of patients diagnosed many years ago. They are often outdated at the time they become available. In this article, we propose a modified product-limit method to obtain up-to-date estimates of long-term survival rates via a period analysis. The proposed method is illustrated with cancer registry data collected from January 1993 to December 1997.

임상시험 연구나 역학 연구에서 환자들의 예후는 흔히 생존을 추정을 통해 수량화 되곤 한다. 하지만 코호트 분석이나 완전분석에 의한 생존율 추정량들은 수년 전에 진단된 환자에 크게 의존하기 때문에 실제 생존율보다 더 낮게 추정하곤 한다. 본 연구에서는 최근의 생존정보를 잘 반영하는 생존을 추정을 위해 기간분석 방법을 통한누적한계 추정량을 제안하였고, 그 방법을 1993년 1월-1997년 12월 사이에 조사된 서울시 암등록 자료(Ahn등, 2002)에 적용하여 결과를 고찰하였다.

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References

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