Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
권호 표지
DOI QR코드

DOI QR Code

Free radical scavenging activity of some Mangroves available in Bangladesh

  • Published : 2006.03.30
Download PDF
⟨ Previous Next ⟩

Abstract

The crude alcoholic extracts of various parts of five different Bangladeshi mangrove plants (Amoora cucullata, Caesalpinia bonducella, Cerbera odollam, Derris uliginosa and Sonneratia caseolaris) were screened in-vitro for anti-oxidant activity using the 1,1-diphenyl-2-picryldydrazyl-hydrate (DPPH) free radical scavenging assay. Of all of them, the ethanolic extracts of the leaves of Derris uliginosa and Sonneratia caseolaris showed potential antioxidant activity ($IC_{50}$: 94.406 and 26.30 mg/ml respectively) whereas the ethanolic extracts of aerial parts of Derris uliginosa, barks of Cerbera odollam and leaves and stems of Caesalpinia bonducella showed moderate activity ($IC_{50}$: 125.89, 211.35 and 301.99 mg/ml respectively). Mild anti-oxidant activity was observed with the methanolic extract of leaves of Amoora cucullata and ethanolic extracts of fruits of Cerbera odollam.

Keywords

References

  1. Abe F, Yamauchi T, Wan Alfred SC. (1988a) Sesqui-, sester-, and trilignans from stems of Cerbera manghas and C. odollam. Phytochemistry 27, 3627-3631. https://doi.org/10.1016/0031-9422(88)80780-5
  2. Abe F, Yamauchi T, Wan Alfred SC. (1988b) Lignans related to olivil from the genus Cerbera (Cerbera. VI). Chem. Pharm. Bull. 36, 795-799. https://doi.org/10.1248/cpb.36.795
  3. Abe F, Yamauchi T, Wan Alfred SC. (1989) Nor-monoterpenoids and their allopyranosides from the leaves of Cerbera species (studied on Cerbera VIII). Chem. Pharm. Bull. 37, 2639-2642. https://doi.org/10.1248/cpb.37.2639
  4. Bandhopadhyau U, Das D, Banerjee RK. (1999) Reactive oxygen species: oxidative damage and pathogenesis. Curr. Sci. 77, 658-666.
  5. Basak UC, Das AB, Das P. (1996) Chlorophyll, carotenoids, proteins, and secondary metabolites in leaves of 14 species of mangroves. Bull. Mar. Sci. 58, 654-659.
  6. Chakrabarti S, Biswas TK, Seal T, Rokeya B, Ali L, Azad Khan AK, Nahar N, Mosihuzzaman M, Mukherjee B. (2005) Antidiabetic activity of Caesalpinia bonducella F. in chronic type 2 diabetic model in Long-Evans rats and evaluation of insulin secretagogue property of its fractions on isolated islets. J. Ethnopharmacol. 97, 117-122. https://doi.org/10.1016/j.jep.2004.10.025
  7. Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN, Ray C. (1968) Screening of Indian plants for biological activity, Pt: 1. Indian J. Exp. Biol. 6, 232.
  8. Evans WC. (1989) Trease and Evan’s Textbook of Pharmacognosy. 13th ed. Cambridge University Press, London, p. 546.
  9. Gayaraja S, Shinde S, Agarwal, SL. (1978) Antiasthmatic properties of Caesalpinia bonducella leaves. Indian J. Pharm. 10, 86.
  10. Gupta M, Mazumder UK, Kumar RS, Sivakumar T, Vamsi ML. (2004) Antitumor activity and antioxidant status of Caesalpinia bonducella against Ehrlich ascites carcinoma in Swiss albino mice. J. Pharmacol. Sci. 94, 177-184. https://doi.org/10.1254/jphs.94.177
  11. Gupta M, Mazumdar UK, Sivahkumar T, Vamis MLM, Karki S, Sambathkumar R, Manikandan L. (2003) Antioxidant and anti-inflammatory activities of Acalypha fruticosa. Nig. J. Nat. Prod. Med. 7, 25-29.
  12. Halliwell H. (1994) Free radicals, antioxidants, and human disease: Curiosity, cause or consequence? Lancet 344, 721-724. https://doi.org/10.1016/S0140-6736(94)92211-X
  13. Halliwell B, Gutteridge JMC. (1985) Free radicals. In Biology and Medicine, 2nd ed., Clarendron Press, Oxford, pp. 279-315.
  14. Hien TI, Navarro-Delmasure C, Vy T. (1991) Toxicity and effects on the central nervous system of a Cerbera odollam leaf extract. J. Ethnopharmacol. 34, 201-206. https://doi.org/10.1016/0378-8741(91)90038-F
  15. Hogg RW, Gillan FT. (1984) Fatty acids, sterols and hydrocarbons in the leaves from eleven species of Mangrove. Phytochemistry 23, 93-97. https://doi.org/10.1016/0031-9422(84)83084-8
  16. Iyengar MA, Pendse GS. (1965) Anti-diarrhoeal activity of the nut of Caesalpinia bonducella (F). Indian J. Pharmacol. 27, 307-308.
  17. Kirtikar KR, Basu BD. (1987) Indian Medicinal Plants. 2nd ed. International Book Distributors, India.
  18. Larson RA. (1988). The antioxidants of higher plants. Phytochemistry 27, 969-978. https://doi.org/10.1016/0031-9422(88)80254-1
  19. Laphookhieo S, Cheenpracha S, Karalai C, Chantrapromma S, Rat-a-Pa Y, Ponglimanont C, Chantrapromma K. (2004) Cytotoxic cardenolide glycoside from the seeds of Cerbera odollam. Phytochemistry 65, 507-510. https://doi.org/10.1016/j.phytochem.2003.10.019
  20. Meow-Chan V, Choo-Loh L. (1987) n-Alkanes of the leaves of some Mangrove plants. UNESCO regional seminar on the chemistry of Mangrove plants, Bangkok, Thailand.
  21. Neogi NC, Nayak KP. (1958) Biological investigation of Caesalpinia bonducella Flem. Indian J. Pharm. 20, 95-100.
  22. Pascoe KO, Burke BA, ChanWR.(1986) Caesalpin F.:a new furanoditerpene from Caesalpinia bonducella. J. Nat. Prod. 49, 913-915. https://doi.org/10.1021/np50047a025
  23. Rollet B. (1981) Bibliography of Mangrove research. 1600-1975. UNESCO Paris. Pub. Information Retrieval Ltd., London, p. 479.
  24. Sadhu SK, Okuyama E, Fujimoto H, Ishibashi M. (2003) Separation of Leucas aspera, a medicinal plant of Bangladesh, guided by Prostaglandin inhibitory and Antioxidant activities. Chem. Pharm. Bull. 51, 595-598. https://doi.org/10.1248/cpb.51.595
  25. Sharma SR, Dwivedi SK, Swarup D. (1997) Hypoglycaemic, antihyperglycaemic and hypolipidemic activities of Caesalpinia bonducella seeds in rats. J. Ethnopharmacol. 58, 39-44. https://doi.org/10.1016/S0378-8741(97)00079-2
  26. Sreejayan N, Rao MNA. (1997) Nitric oxide scavenging by curcuminoids. J. Pharm. Pharmacol. 49, 105-107. https://doi.org/10.1111/j.2042-7158.1997.tb06761.x
  27. Tripathi YB, Chaurasia S, Tripathi E, Upadhyay A, Dubey GP. (1996) Bacopa monniera Linn. As an antioxidant: Mechanism of action. Indian J. Exp. Biol. 34, 523-526.
  28. Vani T, Rajani M, Sarkar S, Shishoo CJ. (1997) Antioxidant properties of the Ayurvedic formulation Triphala and its constituents. Int. J. Pharmacognosy 35, 313-317. https://doi.org/10.1080/09251619708951274
  29. Yamauchi T, Abe F, Wan Alfred SC. (1987a) Cardenolide monoglycosides from the leaves of Cerbera odollam and Cerbera manghas (Cerbera III). Chem. Pharm. Bull. 35, 2744-2749. https://doi.org/10.1248/cpb.35.2744
  30. Yamauchi T, Abe F. (1987b) Studies on Cerbera IV, polar cardenolide glycoside from the leaves of Cerbera odollam and Cerbera manghas. Chem. Pharm. Bull. 35, 4813-4818. https://doi.org/10.1248/cpb.35.4813
  31. Yamauchi T, Abe F, Wan Alfred SC. (1987c) Study on Cerbera. V. Minor glycosides of 17-digitoxigenin from the stems of the genus Cerbera. Chem. Pharm. Bull. 35, 4993-4995. https://doi.org/10.1248/cpb.35.4993

Cited by

  1. Pharmacological Evaluation of Bangladeshi Medicinal Plants for Antioxidant Activity vol.46, pp.10-11, 2008, https://doi.org/10.1080/13880200802215735