동의신경정신과학회지 (Journal of Oriental Neuropsychiatry)

  • 제17권1호
  • /
  • Pages.79-105
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  • 2006
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  • 1226-6396(pISSN)
  • /
  • 2234-4942(eISSN)
대한한방신경정신과학회 (The Korean Society of Oriental Neuropsychiatry)
권호 표지

총명탕(聰明湯)과 향부자총명탕(香附子聰明湯)의 추출물, 나노분말 제형을 이용한 치매에 관한 연구

A Study of ChongMyungTang(CMT) and HyangbujaChongMyungTang(HCMT) on Dementia - Extract & Nano Powder Drug types

  • 오영진 (동의대학교 한의과대학 신경정신과학 교실) ;
  • 김보경 (동의대학교 한의과대학 신경정신과학 교실,동의으료원 한방신경정신과)
  • Oh, Young-Jin (Dept. of Neuropsychiatry, college of oriental medicine, dongeui university) ;
  • Kim, Bo-Kyung (Dept. of Neuropsychiatry, college of oriental medicine, dongeui university)
  • 발행 : 2006.03.30
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초록

Objective : This research aims to investigates the effects of CMT and HCMT on Dementia. and we also want to know the different effect of CMT, HCMT by drug types. Methods : The research is progressed by two types of experiment. one experiment is BV2 microglial cell line treated by LPS in vitro and another experiment is memory deficit mice induced by scopolamine in vivo. Results : The CMT and HCMT is effective in BV2 microglial cell line treated by LPS in vitro and in the serum of the memory deficit mice induced by scopolamine in vivo. But, there is no significant difference between CMT and HCMT extract&nano powder in experimental conclusion. Conclusions : These results suggest that the two drug types of CMT and HCMT may be effective for the prevention and treatment of Dementia. Investigation into the further study two drug types of the CMT and HCMT for Dementia is suggested for future research.

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