동의신경정신과학회지 (Journal of Oriental Neuropsychiatry)
- 제17권1호
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- Pages.37-57
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- 2006
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- 1226-6396(pISSN)
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- 2234-4942(eISSN)
총명탕(聰明湯)과 목근피총명탕(木槿皮聰明湯)이 CT105와 ${\beta}A$ 로 유도된 Alzheimer's Disease 병태(病態) 모델에 미치는 영향
The Effects of ChongMyungTang(CMT) and ChongMyungTang added Hibiscus syriacus(MCMT) Extract on the Alzheimer's Disease Model Induced by CT-105 and ${\beta}A$
- Park, Ji-Un (Dept. of Oriental Neuropsychiatry College of Oriental Medicine, Daejeon University) ;
- Jung, In-Chul (Dept. of Oriental Neuropsychiatry College of Oriental Medicine, Daejeon University) ;
- Lee, Sang-Ryong (Dept. of Oriental Neuropsychiatry College of Oriental Medicine, Daejeon University)
- 발행 : 2006.03.30
초록
Objective : This research investigates the effect of the CMT and MCMT on Alzheimer‘s disease. Methods : The effects of the CMT and MCMT extract on (1) amyloid precursor proteins(APP), acetylcholinesterase(AChE) mRNA of PC-12 cells treated with CT-105; (2) the AChE activity and the APP production of PC-12 cell treated with CT-105; (3) the behavior; (4) expression of