References
- Brown, K. G., Fink, G., and Murray, M. A. F., Altered sexual development in male rats after estrogen administration during the neonatal period. J. Reprod. Ferti., 44, 25-42 (1975) https://doi.org/10.1530/jrf.0.0440025
- Chaffin, C. L., Peterson, R. E., and Hutz, R. J., In utero and lactational exposure of female Holtzman rats to 2,3,7,8-tetrachlorodaibenzo-p-dioxin: Modulation of the estrogen signal. Biol. Reprod., 55, 62-67 (1996) https://doi.org/10.1095/biolreprod55.1.62
- Court, W. A., Hendel, J. G., and Elmi, J., Reversed-phase highperformance liquid chromatographic determination of ginsenosides of Panax quinquefolium. J. Chromatography A., 755, 11-17 (1996) https://doi.org/10.1016/S0021-9673(96)00580-8
- Fraga, C. G., Motchnik, P. A., and Shigenaga, M. K., Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc. Natl. Acad. Sci., 88, 11003-11006 (1991)
- Furuya, T. and Yoshikaya, T., Saponin production by cultures of Panax ginseng transformed with Agrobacterium rhizogenes. Plant Cell Rep., 6, 449-453 (1987)
- Geva, E., Bartoov, B., and Zabludovsky, N., The effect of antioxidant treatment on human spermatozoa and fertilization rate in an in vitro fertilization program. Fertil. Steril., 66, 430– 434 (1996) https://doi.org/10.1016/S0015-0282(16)58514-8
- Hahn, E. J., Kim, Y. S., Yu, K. W., Jeong, C. S., and Paek, K. Y., Adventitious root cultures of Panax ginseng C.A. Meyer and Ginsenoside production through large-scale bioreactor system. J. Plant. Biotechnol., 5, 1-6 (2003)
- Hwang, S. Y., Yang, J. B., Wee, J. J., Kim, O. H., and Kim, S. K., Crude saponin from Korean red ginseng attenuates testicular toxicity of rats exposed to 2,3,7,8-tetrachlorodibenzo-pdioxin, J. Ginseng Res., 27, 171-177 (2003) https://doi.org/10.5142/JGR.2003.27.4.171
- Johnson, L., Dickerson, R., Safe, S. H., Nyberg, C. L., Lewis, R. P., and Welsh, T. H., Reduced Leydig cell volume and function in adult rats exposed to 2,3,7,8-tetrachlorodaibenzop- dioxin without a significant effect on spermatogenesis. Toxicology, 76, 103-118 (1992) https://doi.org/10.1016/0300-483X(92)90158-B
- Lewin, A. and Lavon, H., The effect of coenzyme Q10 on sperm motility and function. Mo. Aspects Med., 18, Suppl: S213-219 (1997) https://doi.org/10.1016/S0098-2997(97)00036-8
- Mably, T., Bjerke, D.L., Moore, R. W., Gendron-Fitzpatrick, A., and Peterson, R. E., In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodaibenzo-p-dioxin. III. Effects on spermatogenesis and reproductive capability. Toxicol. Appl. Pharmacol., 114, 118-126 (1992 c) https://doi.org/10.1016/0041-008X(92)90103-Y
- Matsuda, H., Samukawa, K., and Kubo, M., Anti-inflammatory activity of ginsenoside Ro. Planta Med., 56, 19-23 (1990) https://doi.org/10.1055/s-2006-960875
- Matsuda, H., Samukawa, K., and Kubo, M., Anti-hepatic activity of ginsenoside Ro. Planta Med., 57, 523-526 (1991) https://doi.org/10.1055/s-2006-960198
- Mebus, C. A., Reddy, V. R., and Piper, W. N., Depression of rat testicular 17-hydroxylase and 17,20-lyase after administration of 2,3,7,8-tetrachloro daibenzo-p-dioxin (TCDD). Biochem. Pharmacol., 36, 727-731 (1987) https://doi.org/10.1016/0006-2952(87)90726-X
- Ohnishi, Y., Tagaki, S., and Miura, T., Effect of ginseng radix on GLUT2 protein content in mouse liver in normal and epinephrine-induced hyperglycemic mice. Biol .Pharm. Bull., 19, 1238-1240 (1996) https://doi.org/10.1248/bpb.19.1238
- Oshima, Y., Sato, K., and Hikino, H., Isolation and hypoglycemic activity of quinquefolans A, B, and C, glycans of Panax quinquefolium roots. J .Nat. Prod., 50, 188-190 (1987) https://doi.org/10.1021/np50050a010
- Peterson, R. E., Theobald, H. M., and Kimmel, G. L., Developmental and reproductive toxicity of dioxins and related compounds: Cross-species comparisons. Crit. Rev. Toxicol., 23, 283-335 (1993) https://doi.org/10.3109/10408449309105013
- Rolf, C., Cooper, T. G., Yeung, C. H., and Nieschlag, E., Antioxidant treatment of patients with asthenozoospermia or moderate oligoasthenozoospermia with high-dose vitamin C and vitamin E: a randomized, placebo-controlled, doubleblind study. Hum. Reprod., 14, 1028-1033 (1999) https://doi.org/10.1093/humrep/14.4.1028
- Rune, G. M., de Souza, Ph., Krowkw, R., Merker, H. J., and Neubert, D., Morphological and histochemical pattern of response in rat testes after administration of 2,3,7,8- tetrachlorodaibenzo-p-dioxin(TCDD). Histol. Histopathol., 6, 459-467 (1991)
- Salvati, G., Genovesi, G., and Marcellini, L., Effects of Panax ginseng C.A. Meyer saponins on male fertility. Panmineva. Med., 38, 249-254 (1996)
- Sandler, B. and Faragher, B., Treatment of oligospermia with vitamin B12. Infertility, 7, 133-138 (1984)
- Scaglione, F., Cattaneo, G., Alessandria, M., and Cogo, R., Efficacy and safety of the standardised ginseng extract G115 for potentiating vaccination against the influenza syndrome and protection against the common cold. Drugs Exp. Clin. Res., 22, 65-72 (1996)
- Schacter, A., Goldman, J. A., and Zukerman, Z., Treatment of oligospermia with the amino acid arginine. J. Urol., 110, 311- 313 (1973) https://doi.org/10.1016/S0022-5347(17)60199-X
- Scott, R., MacPherson, A., and Yates, R. W. S., The effect of oral selenium supplementation on human sperm motility. Br. J. Urol., 82, 76-80 (1998) https://doi.org/10.1046/j.1464-410x.1998.00683.x
- Sommer, R. J., Ippolito, D. L., and Peterson, R. E., In utero and lactational exposure of the male Holtzman rats to 2,3,7,8-tetrachlorodaibenzo-p-dioxin: Decreased epididymal and ejaculated sperm numbers without alterations in sperm transit rate. Toxicol. Appl. Pharmacol., 140, 146-153 (1996) https://doi.org/10.1006/taap.1996.0207
- Toth, G. P., Zenick, H., and Smith, M. K., Effects of epichlorohydrin on male and female reproduction in Long- Evans rats. Fundam. Appl. Toxicol., 13, 16-25 (1989) https://doi.org/10.1016/0272-0590(89)90303-5
- Yun, T. K., Panax ginseng - a non-organ-specific cancer preventive Lancet Oncol., 2, 49-55 (2001) https://doi.org/10.1016/S1470-2045(00)00196-0
- Yun, T. K. and Choi, S. Y., Non-organ specific cancer prevention by ginseng: a prospective study in Korea. Int. J. Epidemiol., 27, 359-364 (1998) https://doi.org/10.1093/ije/27.3.359
- Yves, C. and Bernard, P. C., Quantitative study of the cell population of the seminiferous tubles in immature rats. Am. J .Anat., 100, 241-260 (1969) https://doi.org/10.1002/aja.1001000205
- Zuin, M., Battezzati, P. M., Camisasca, M., Riebenfeld, D., and Podda, M., Effects of a preparation containing a standardised ginseng extract combined with trace elements and multivitamins against hepatotoxin-induced chronic liver disease in the elderly. J. Int. Med. Res., 15, 276-281 (1987) https://doi.org/10.1177/030006058701500503