Journal of Acupuncture Research
- 제23권5호
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- Pages.23-29
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- 2006
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- 2586-288X(pISSN)
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- 2586-2898(eISSN)
신경병증성 통증에 대한 자동염전침의 진통효과 및 opioid 기전
The Effects of Automatically Controlled Rotating Acupuncture on Thermal Allodynia in a Rat Model of Neuropathic Pain: Mediation by Endogenous Opioid System
- 박정혁 (경희대학교 대학원 학과간협동과정 동서의학과) ;
- 김선광 (경희대학교 대학원 학과간협동과정 동서의학과) ;
- 나효석 (경희대학교 대학원 학과간협동과정 동서의학과) ;
- 문학진 (경희대학교 대학원 학과간협동과정 동서의학과) ;
-
민병일
(경희대학교 대학원 학과간협동과정 동서의학과) ;
- 김기홍 (경희대학교 공과대학 기계공학과) ;
-
임성수
(경희대학교 공과대학 기계공학과) ;
-
이순걸
(경희대학교 공과대학 기계공학과) ;
-
이상훈
(경희대학교 한의과대학 침구학교실)
- Park, Jung-Hyuk (Department of East-West Medicine, Graduate School, Kyung Hee University) ;
- Kim, Sun-Kwang (Department of East-West Medicine, Graduate School, Kyung Hee University) ;
- Na, Hyo-Suk (Department of East-West Medicine, Graduate School, Kyung Hee University) ;
- Moon, Hak-Jin (Department of East-West Medicine, Graduate School, Kyung Hee University) ;
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Min, Byung-Il
(Department of East-West Medicine, Graduate School, Kyung Hee University) ;
- Kim, Ki-Hong (Department of Mechanical Engineering, College of Advanced Technology, Kyung Hee University) ;
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Rhim, Sung-Soo
(Department of Mechanical Engineering, College of Advanced Technology, Kyung Hee University) ;
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Lee, Soon-Geul
(Department of Mechanical Engineering, College of Advanced Technology, Kyung Hee University) ;
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Lee, Sang-Hoon
(Department of Acupuncture & Moxibustion, College of Oriental Medicine, Kyung Hee University)
- 발행 : 2006.10.20
초록
Objectives : The present study was conducted to evaluate the effects of automatically controlled rotating acupuncture (ACRA) on thermal allodynia in neuropathic pain rats, and to examine whether the endogenous opioid system mediates the effects of ACRA. Methods : For the neuropathic surgery, the right superior caudal trunk was resected at the level between S1 and S2 spinal nerves innervating the tail. Two weeks after the nerve injury, ACRA stimulation with 4 different stimulation conditions (i.e., angle and frequency of rotation: 90o+1Hz, 90o+1/4Hz, 360o+/1Hz, and 360o+1/4Hz) was delivered to the Zusanli (ST36) acupoint for 15 min. The behavioral signs of thermal allodynia were evaluated by the tail immersion test (i.e., immersing the tail in cold