Korean Journal of Biological Psychiatry (생물정신의학)
- Volume 12 Issue 1
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- Pages.13-19
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- 2005
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- 1225-8709(pISSN)
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- 2005-7571(eISSN)
Heart Rate Variability of Korean Generalized Anxiety Disorder Patients
한국 범불안장애 환자의 자율신경심장기능
- Choo, Chung-Sook (Department of Psychiatry, Ilsanpaik Hospital, Inje University of Korea) ;
- Lee, Seung-Hwan (Department of Psychiatry, Ilsanpaik Hospital, Inje University of Korea) ;
- Kim, Hyun (Department of Psychiatry, Ilsanpaik Hospital, Inje University of Korea) ;
- Lee, Kang-Joon (Department of Psychiatry, Ilsanpaik Hospital, Inje University of Korea) ;
- Nam, Min (Department of Psychiatry, Ilsanpaik Hospital, Inje University of Korea) ;
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Chung, Young-Cho
(Department of Psychiatry, Ilsanpaik Hospital, Inje University of Korea)
- 추정숙 (인제대학교 의과대학 일산백병원 신경정신과학교실) ;
- 이승환 (인제대학교 의과대학 일산백병원 신경정신과학교실) ;
- 김현 (인제대학교 의과대학 일산백병원 신경정신과학교실) ;
- 이강준 (인제대학교 의과대학 일산백병원 신경정신과학교실) ;
- 남민 (인제대학교 의과대학 일산백병원 신경정신과학교실) ;
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정영조
(인제대학교 의과대학 일산백병원 신경정신과학교실)
- Published : 2005.05.31
Abstract
Objective:The purposes of this study were to investigate heart rate variability(HRV) in patients with generalized anxiety disorder(GAD) compared with major depressive disorder in Korea. Methods:Fifty-six GAD patients(20 male and 36 female) was classified into their comorbid psychiatric illness. Among them, Twenty-five patients(10 male and 15 female) who do not have any psychiatric comorbidity were compared with 30 major depressive disorder patients(12 male and 18 female). Clinical symptoms, HRV and MMPI were analysed between two group. Results:Comorbid psychiatric illnesses of GAD were ranked into no diagnosis(44.6%), MDD(32.1%), panic disorder(10.7%), social phobia(5.3%), PTSD(1.7%), OCD(1.7%), MDD+panic disorder(1.7%) and MDD+specific phobia(1.7%). GAD patients showed low functioning in HRV, but degree of decreasing HRV is not so severe compared with MDD patient. Balance of sympathetic and parasympathetic nerve tone is more severely impaired in GAD patients compared with MDD patient. The score of MMPI did not reveal any differences between two groups. Conclusions:The result showed that HRV can differenciate GAD and MDD patients. GAD patients could show decreased HRV functioning, less than MDD patients. But autonomic imbalance could be more severe in GAD than MDD patients.
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