The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
권호 표지

Effect of Deer Antler on the Inhibitory Action of Obese Rats

녹용이 흰쥐의 비만억제에 미치는 영향

  • Jun Chan-Il (Dept. of Pediatrics, College of Oriental Medicine, Kyung Hee University) ;
  • Lee Jin-Yong (Dept. of Pediatrics, College of Oriental Medicine, Kyung Hee University) ;
  • Kim Deog-gon (Dept. of Pediatrics, College of Oriental Medicine, Kyung Hee University)
  • 전찬일 (경희대학교 한의학대학 소아과교실) ;
  • 이진용 (경희대학교 한의학대학 소아과교실) ;
  • 김덕곤 (경희대학교 한의학대학 소아과교실)
  • Published : 2005.03.01
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: We investigated the effects of deer antler extract (DAE) on the expression of the weight, leptin, and serum levels (lipid metabolism) of the obese SD rats induced by a $2\%$ cholesterol diet in vivo. Methods: In vivo, the weight, leptin and serum levels were measured after a period of 7 weeks for obese SD rats induced by a $2\%$ cholesterol diet and treated with DAE of three concentrations (0.938 g/kg/5ml, 1.875 g/kg/5ml, 3.75 g/kg/5ml). Results: 1. Body weight didn't change significantly. 2. Leptin levels significantly decreased (p<0.05). 3. Total cholesterol, triglyceride, LDH, sGOT & sGPT levels significantly decreased in the sample (p<0.05). 4. The HDL cholesterol levels significantly increased in the sample (p<0.05). 5. The average size of the epididymal fat cells significantly decreased as the concentration of deer antler extract increased (p<0.05). Conclusion: Deer antler effects inhibition of obese rats.

Keywords