Relationship between morphology and viscosity of the main culture broth of Cephalosporium acremonium M25

  • Kim Jong Chae (Department of Chemical and Biological Engineering, Korea University) ;
  • Lim Jung Soo (Department of Chemical and Biological Engineering, Korea University) ;
  • Kim Jung Mo (Department of Chemical and Biological Engineering, Korea University) ;
  • Kim Chongyoup (Department of Chemical and Biological Engineering, Korea University) ;
  • Kim Seung Wook (Department of Chemical and Biological Engineering, Korea University)
  • Published : 2005.03.01

Abstract

In this study, the relationship between morphology and viscosity of the main culture broth of Cephalosporium acremonium M25 was investigated in a 2.5 L bioreactor. The differentiation of C. acremonium M25 showed a complex pattern during the main culture. The morphological changes of C. acremonium M25 were related to the rheological properties of the culture broth and it was well agreed with the power law model. As a result of rheology study, it was found that rheological properties of the main culture broths of C. acremonium M25 in bioreactor were closely related to morphological changes. Also, fractal dimension fairly predicted morphological and rheological changes in the main culture broth.

Keywords

References

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