Mineral Intakes and Serum Mineral Concentrations of the Pregnant and Lactating Women

임신$\cdot$수유부의 무기질 섭취와 혈청 무기질 함량에 관한 연구

  • Kim Wooo Ju (Department of Food and Nutrition, Chungbuk National University) ;
  • Ahn Hong Seok (Department of Food and Nutrition, Sungshin Women s University) ;
  • Chung Eun Jung (General Education, Kangnam University)
  • 김운주 (충북대학교 생활과학대학 식품영양학과) ;
  • 안홍석 (성신여자대학교 생활과학대학 식품영양학과) ;
  • 정은정 (강남대학교 교양학부)
  • Published : 2005.02.01

Abstract

The purpose of this study was to estimate the mineral intakes and serum mineral levels of pregnant and lactating women. The subjects consisted of 34 non-pregnant, 56 pregnant and 20 lactating women. Nutrients intakes were investigated by the 24-hr recall method, and serum major and trace minerals were analyzed by the ICP-spectrometry. Calcium (Ca) and zinc (Zn) intakes were observed lower than RDA especially for both pregnant and lactating women. Iron (Fe) intake of pregnant women was $85 - 139\%$ RDA through Fe supplementation, and that of lactating women was lower than RDA. Compared with non-pregnant women, the pregnant women had similar Ca intake and higher magnesium (Mg) intake. Comparing with the non-pregnant women, serum Ca level in pregnancy was lower, and that of lactating women was not significantly different. Serum phosphorus and Mg levels were not significantly different among the groups. Serum Fe level of pregnant and lactating women was lower than that of the non-pregnant women. Serum Zn level of pregnant women was lower than those in the lactating and non-pregnant women. Serum copper level decreased as the pregnancy progressed. Serum sodium (Na) level was higher in 2nd- and 3rd trimester and potassium (K) level was higher in 3rd trimester and lactating period than other groups. Na/K ratio was not significantly different among the groups. During all periods, there was no correlation between dietary intakes and serum levels in each minerals. Serum Ca level positively corrleated with serum Mg level, especially in 3rd trimester and lactating women. In general, serum mineral levels in pregnancy were changed compared to the levels in non-pregnancy and restored in lactation to the levels for non-pregnancy.

Keywords

References

  1. 김상순, 김순경 (1988): 단백질 섭취수준이 인체 내 칼슘, 인, 마그네슘 대사에 미치는 영향에 관한 연구. 숙명여자대학교 생활과학연구소 논문집 2: 59-103
  2. 김은경, 남혜원, 박영심, 명춘옥, 이기완 (2001): 생활주기영양학, 신광출판사
  3. 한국식품공업협회 식품연구소 (1988): 식품 섭취실태 조사를 위한 식품 및 음식의 눈대중량
  4. Ahn HS, Choi MK (1993): Influence of maternal diet in mineral and trace element contents of human milk and relationships between level of these milk constituents. Kor J Nutr 26 (6) : 772-782
  5. Ahn HS, Lee JY (2001): Comparison of mineral contents in colostrum of the mothers with fullterm, preterm delivery and pregnancy induced hypertension. Kor J Nutr 34 (6) : 656-663
  6. Ahn HS, Lee GJ, Hong HK, Chung SW, Yang JH, Chung HW (2001): Serum vitamin $B_{12}$ levels of maternal-umbilical cord blood and pregnancy outcomes. Kor J Nutr 34 (4) : 426- 432
  7. Ahn HS, Moon SJ, Park SH, Lee MJ (1995): Lactation and weaning practices of the Korean mothers. Infant Nutrition Proceeding of 2nd Int'l Sym, pp.92-115
  8. Ahn HS, Park SH (1999): Maternal serum zinc concentration and pregnancy outcomes. Kor J Nutr 32(2): 182-188
  9. Anastasiadis P, Rimpler M (1984): Sodium and potassium concentrations in whole blood and the serum of pregnant females and newborn infants. Zentralbl Gynakol 106(2): 101-113
  10. Apgar J (1975): Effects of some nutritional deficiencies on partuition in rats. J Nutr 105: 1553-1561 https://doi.org/10.1093/jn/105.12.1553
  11. Brennan RE, Kohrs MB, Nordstrom JW, Sauvage JP, Shank R (1983): Composition of diets of low-income pregnant women: comparison of analyzed with caculated values. J Am Diet Assoc 83: 538-545
  12. Ekeke GI, Ebirim UA (1986): Serum sodium and potassium values in pregnant urban Nigerian and Caucasian women. Trop Geogr Med 38 (1) : 28-32
  13. Gilstrap LC, Gant NF (1990): Pathophysiology of preeclampsia. Semin Perinatology 14: 147-151
  14. Giroux E, Schechter PJ, Schoun J (1976): Diminished albumin binding of zinc in serum of pregnant women. Clin Sci Mol Med 51: 545-549
  15. Grarett MG (1984): Cause of preterm delivery. Semin Perinatology 8: 246-457
  16. Hurley LS (1975): Trace elements and teratogenesis, symposium on biochemical and nutritional aspects of trace elements. Med Clines N Am 60: 771-778
  17. Jacobson S, Wester PO (1977): Balance Study of twenty trace elements during total parenterl nutrition in man. Br J Nutr 77: 107-125
  18. Johnson AA, Knight EM, Edwards CH, Oyemade UJ, Cole OJ, Weatney OE, Westney LS, Laryea H, Jones S (1994): Dietary intakes, anthropometric measurements and pregnancy outcomes. J Nutr 124 (suppl) : 936S-942S
  19. Knight KB, Keith RE (1992): Calcium supplementation on normotensive and hypertensive pregnant women. Am J Clin Nutr 55 (4): 891-895 https://doi.org/10.1093/ajcn/55.4.891
  20. Koski KG, Mancini M (1990): Influence of carbohydrate-restricted versus calorie-restricted diets on rat placental glycogen. Nutr Res 10: 63-68 https://doi.org/10.1016/S0271-5317(05)80766-3
  21. Lee EJ, Kim MH, Cho MS, Kim YJ, Kim HY (2003): A study on nutrient intakes and hematological status in women of child bearing age: Comparison between non-pregnant and pregnant women. Kor J Nutr 36(2): 191-199
  22. Lee IH, Hong HS (1983): Correaltion of levels of hemoglobin and hematocrit with nutritional intakes and general environmental factors of pregnant women among low income group in seoul area. Kor Home Economic Asso 21: 51-64
  23. Lee JS, Kim ES (1998): Study on vitamin E intake of exclusively breastfed infants. Kor J Nutr 31 (9): 1440-1445
  24. Lee KJ, Moon SJ, Lee MJ, Ahn HS (1993): Postpartum changes in maternal diet, body fat and antrtometric measurements in lactating vs nonlactating women. Kor J Nutr 26 (1) : 76-88
  25. Lee YC, Chung EJ, Hwang JA, Kim MK, Lee JH, Park T, Kim ST, Park KS (1998): A study on serum concentrations of antioxidant minerals in normal korean adults. Kor J Nutr 31 (3) : 324-332
  26. Leela R, Yasodhara P, Ramaraju LA (1991): Calcium and magnesium in pregnancy. Nutr Res 11: 1231-1236 https://doi.org/10.1016/S0271-5317(05)80542-1
  27. McMillan JA (1977): Iron absorption from human milk, simulated human milk and proprietary formulas. Pediatrics 60: 896-900
  28. Moon SJ, Kang JS, Lee MJ, Lee JH, Ahn HS (1995): A longitudinal study of micro-mineral concentrations in human milk. Kor J Nutr 28 (7) : 620-628
  29. Mukherjee MD, Sandstead HH, Patnaparkhi MV, Johnson LK, Milne DB, Stelling HP (1984): Maternal zinc, iron, folic acid and protein nutriture and outcome of human pregnancy. Am J Clin Nutr 40: 496-507 https://doi.org/10.1093/ajcn/40.3.496
  30. O'Dell BL (1984) : Bioavailability of trace elements. Nutr Rev 42: 301-308 https://doi.org/10.1111/j.1753-4887.1984.tb02370.x
  31. Olatunbosun DA, Adeniyi FA, Adadevoh BK (1975) : Serum calcium, phosphorus and magnesium levels in pregnant and non-pregnant nigerians. Br J Obstet Gynaecol 82: 568-571 https://doi.org/10.1111/j.1471-0528.1975.tb00688.x
  32. Park SH (1988): A study of iron, copper, zinc, manganese concentrations of Korean pregnant women. Sungshin Women's University. Master's thesis
  33. Prasad AS (1976): Trace elements in human health and disease. Academic Press (Vol 1) :33
  34. Recommended dietary allowances for Korean, 6th revision (1995): The Korean Nutrition Society
  35. Recommended dietary allowances for Korean, 7th revision (2000): The Korean Nutrition Society
  36. Saeed AN (1994): Longitudinal study of serum minerals, electrolytes and hemoglobin during second trimester of pregnancy in Pakistani women. Nutr Res 14(7): 977-989 https://doi.org/10.1016/S0271-5317(05)80252-0
  37. Schenker JG, Jungreis E, Polishuk WZ (1971): Oral contraceptives and serum copper concentration. Obstet Gynecol 37: 233-237
  38. Seung CC (1990): A stydt on Mg status in adult Korean rural women on self-selected diet. Kor J Nutr 23: 25-36
  39. Simopoulos AP (1998): ${\omega}$-3 Fatty acid in growth and development in health and disease. Nutr Today 12-18
  40. Song YS, Kim SH (1989): Nutritional status of rural pregnant women in relation to physical condition of offspring at birth. Kor J Nutr 22: 547-556
  41. Swanson CA, King JC (1983): Reduced serum zinc concentration during pregnancy. Obstet Gynecol 62: 313-318 https://doi.org/10.1097/00006250-198309000-00010
  42. Tuttle S, Aggett PJ, Campbell D (1985): Zinc and copper nutrition in human pregnancy. Am J Clin Nutr 41: 1032-1041 https://doi.org/10.1093/ajcn/41.5.1032
  43. United Stated Department of Agriculture (1990): Composition of Foods 1990
  44. Villar J, Belizan JM (2000): Same nutrient, different hypotheses: disparities in trials of calcium supplementation during pregnancy. Am J Clin Nutr 71 (5): 1375s-1379s
  45. Vuori E, Makinen SL, Kara R, Kuitunen P (1980): The effects of the dietary intakes of copper, iron, manganese, and zinc in the trace element content of human milk. Am J Clin Nutr 33: 227-231 https://doi.org/10.1093/ajcn/33.2.227
  46. Yu KH (2000): The study of zinc nutritional status of pregnant women visiting in public health centers in Ulsan. 33 (8) : 848-856
  47. Yu KH, Yoon JS (1999): A cross-sectional study of nutrient intakes by gestational age and pregnancy outcome (I). Kor J Nutr 32 (8) : 877-886
  48. 科學技術府字源調査會 (1992): 食品成分表, 日本