내과계 중환자실 입원환자의 비,인후 배양에서 메치실린내성 황색포도구균의 빈도

The Methicillin - Resistant Rate of Staphylococcus Aureus Isolated from the Nares and Throat of Patients Admitted to Medical Intensive Care Unit

  • 김희구 (인하대학교 의과대학 내과학교실) ;
  • 조재화 (인하대학교 의과대학 내과학교실) ;
  • 안인선 (인하대학교 의과대학 내과학교실) ;
  • 윤병갑 (인하대학교 의과대학 내과학교실) ;
  • 이금호 (인하대학교 의과대학 내과학교실) ;
  • 류정선 (인하대학교 의과대학 내과학교실) ;
  • 곽승민 (인하대학교 의과대학 내과학교실) ;
  • 이홍렬 (인하대학교 의과대학 내과학교실) ;
  • 김진주 (인하대학교 의과대학 진단검사의학교실)
  • Kim, Hi Gu (Department of Internal Medicine, College of Medicine, Inha University) ;
  • Cho, Jae Hwa (Department of Internal Medicine, College of Medicine, Inha University) ;
  • Ahn, In Sun (Department of Internal Medicine, College of Medicine, Inha University) ;
  • Yoon, Byoung Gap (Department of Internal Medicine, College of Medicine, Inha University) ;
  • Lee, Keum Ho (Department of Internal Medicine, College of Medicine, Inha University) ;
  • Ryu, Jeong Sun (Department of Internal Medicine, College of Medicine, Inha University) ;
  • Kwak, Seung Min (Department of Internal Medicine, College of Medicine, Inha University) ;
  • Lee, Hong Lyeol (Department of Internal Medicine, College of Medicine, Inha University) ;
  • Kim, Jin Joo (Department of Clinical Pathology, College of Medicine, Inha University)
  • 투고 : 2005.03.18
  • 심사 : 2005.07.13
  • 발행 : 2005.08.30

초록

연구 배경 : 황색 포도상구균은 피부, 연조직 감염, 골 관절염, 폐렴, 균혈증, 식중독 등을 일으키는 병원균으로 이로 인한 치료를 하지 못했을 때 높은 이환율과 치환율을 보여주고 있다. 내과계 중환자실로 입원한 환자와 일반 병실로 입원한 환자간의 MRSA에 대한 보균율과 선별검사의 의의를 알아보기 위하여 본 연구를 진행하였다. 방 법 : 2004년 6월부터 9월까지 내과계 중환자실과 일반병실로 입원한 환자를 대상으로 하였다. 내원 24 시간 이내에 비공과 인후에서 배양 검사를 실시하여 양군을 서로 비교하였다. 결 과 : 대상환자는 중환자실 121명과 일반병실 84명이었다. 비공에서의 MRSA 보균율은 중환자실군에서 3명(2.5%), 일반 병실군에서 3명(3.6%)으로 양군에서 차이점은 보이지 않았다. 인후에서의 MRSA 보균율에서는 중환자실군과 일반 병실군에서 각각 2명(1.7%), 0명으로 유의한 차이는 없었다. 입원 경로, 수술 경험, 이전 입원 경험에 대한 조사에서도 MRSA 양성군과 음성인 군에서 차이는 없었다. 결 론 : 내과계 중환자실 입원환자에서 MRSA 보균율은 3.3%였다. 내과계 중환자실로 입원한 환자와 일반 병실 환자에서 MRSA의 보균율에 있어 큰 차이가 없어 MRSA에 대한 선별 검사는 꼭 필요하리라 생각되지 않는다. 앞으로 MRSA 보균의 위험 인자가 있는 환자들을 대상으로 한 MRSA 선별검사에 대한 연구가 필요하다.

Background : Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen in hospital-acquired infection, and is prevalent in intensive care units (ICU). The MRSA colonization rates of the nares and throat were examined in both the ICU and general ward. This study was performed to investigate the MRSA rate and necessity for MRSA screening cultures in patients admitted to ICU. Methods : Between June and September 2004, those patients admitted to both the medical ICU and general ward participated in this study. Bacterial cultures were performed on swabs of the nares and throat taken within 24 hours of admission. Clinical data were also collected. Results : One hundred and twenty one patients and 84 patients, admitted to the medical ICU and medical general ward, respectively, were investigated. The numbers of nasal MRSA colonization in the ICU and general ward were 3 (2.5%) and 3 (3.6%), respectively. There were 2 (1.7%) cases of throat MRSA colonization in the ICU, but none in the general ward. The MRSA colonization rates of the nares and throat were no different between the ICU and general ward. There were no significant differences in the previous admission, operation history and admission route between the ICU and general ward groups. Conclusion : The MRSA colonization rates of the nares and throat were 3.3 and 3.6% in the ICU and the general ward, respectively. The MRSA screening test does not appear to be required in all patients admitted to the ICU, but further studies, including high-risk patients, are recommended.

키워드

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