Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Insidious Onset of Amiodarone Pulmonary Toxicity Presented with Hemoptysis

객혈 양상으로 발현된 Amiodarone 폐독성 1예

  • Kim, Hearn Kook (Department of Internal Medicine, University of Ulsan, Gangneung Asan Hospital) ;
  • Jung, Bock Hyun (Department of Internal Medicine, University of Ulsan, Gangneung Asan Hospital) ;
  • Han, Kun Hee (Department of Internal Medicine, University of Ulsan, Gangneung Asan Hospital) ;
  • Hwang, Jung Won (Department of Internal Medicine, University of Ulsan, Gangneung Asan Hospital) ;
  • Cho, Young Ju (Department of Internal Medicine, University of Ulsan, Gangneung Asan Hospital) ;
  • Park, Yong Jin (Department of Internal Medicine, University of Ulsan, Gangneung Asan Hospital) ;
  • Jung, Hyoung Jung (Department of Internal Medicine, University of Ulsan, Gangneung Asan Hospital) ;
  • Kim, Mi Hye (Department of Internal Medicine, University of Ulsan, Gangneung Asan Hospital) ;
  • Ryu, Dae Sik (Department of Diagnostic Radiology, University of Ulsan, Gangneung Asan Hospital) ;
  • Kang, Gil Hyun (Department of Diagnostic Pathology University of Ulsan, Gangneung Asan Hospital)
  • 김헌국 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 정복현 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 한군희 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 황정원 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 조영주 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 박용진 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 정형정 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 김미혜 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 류대식 (울산대학교 의과대학 강릉아산병원 진단방사선과) ;
  • 강길현 (울산대학교 의과대학 강릉아산병원 진단병리과)
  • Received : 2005.06.28
  • Accepted : 2005.08.23
  • Published : 2005.10.30
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Abstract

Amiodarone is widely used to control fatal arrhythmia. However, amiodarone therapy is associated with a relatively high incidence of pulmonary toxicity, up to 5 to 10%. Typical symptoms are nonspecific and often manifest as nonproductive cough, dyspnea and interstitial infiltrates in patients with acute pneumonitis or chronic fibrosis. However, hemoptysis is a very rare symptom of amiodarone pulmonary toxicity. We report a case of amiodarone pulmonary toxicity, who presented with hemoptysis and was successfully treated with the cessation of amiodarone, with review of the relevant literature.

Amiodarone을 사용하는 환자에서 객혈이 발생하였을 경우 원인으로 amiodarone의 폐독성을 반드시 고려하여야 하며 즉시 투여를 중지하고 스테로이드를 사용하면 임상 증상을 호전시킬 수 있다. 저자들은 저용량의 amiodarone을 장기간 사용하던 환자에서 발생한 객혈을 약물 투여 중지 및 대증적 치료로 호전시킨 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

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