Transactions of the Korean Society of Mechanical Engineers B (대한기계학회논문집B)

The Korean Society of Mechanical Engineers (대한기계학회)
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Numerical Study on Characteristics of Pulsitile Flow by Location of Stenosis in Blood Vessel with the Second Bifurcation

2차 분지가 있는 혈관에서 협착의 위치에 따른 맥동 유동 특성에 대한 수치해석 연구

  • 이인섭 (중앙대학교 미래신기술연구소) ;
  • 유홍선 (중앙대학교 기계공학부)
  • Published : 2005.01.01
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Abstract

The main objective of the present study is to predict characteristics of three dimensional pulstitile flow by location of stenosis in blood vessel with the second order bifurcation. The present study simulates the incompressible non-Newtonian laminar blood flows using a Fluent V. 6.0. The Carreau model is employed as the constitutive equation for blood. The numerical simulation carried out at five cases without and with symmetry or asymmetry stenosis. It is found that the no stenosis and stenosis before first bifurcation do not have influence on flow at second bifurcated blood vessel. However, the stenosis after first biburcation has effect on flow at second bifurcated blood vessel.

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References

  1. Fry, D. L., 1972, 'Response of the Arterial Wall to Certain Physical Factors. Atherogenesis: Initiating Factors,' A Ciba Foundation Symp., ASP, Amsterdam, The Neterlands, pp. 40-83
  2. Caro, C. G., Fitz-Gerald, J. M. and Schroter, R. C., 1971, 'Atheroma and Arterial Wall Shear: Observation, Correlation and Proposal of a Shear Dependent Mass Transfer Mechanism for Atherogenesis,' Proc. R. Soc., Ser. B, Vol. 177, pp. 109-159 https://doi.org/10.1098/rspb.1971.0019
  3. Ku, D. N., Giddens, D. P., Zarins, C. K. and Glagov, S., 1985, 'Pulsatile Flow and Atherosclerosis in the Human Carotid Bigurcation. Positive Correlation Between Plague Location and & Low and Oscillating Shear Stress,' Arteriosclerosis, pp. 293-302
  4. Lei, M., Kleinstreuer, C. and Truskey, G. A., 1995, 'Numerical Investigation and Prediction of Atherogenic Sites in Branching Arteries,' ASME Journal of Biomechanical Engineering, Vol. 117, pp. 350-357 https://doi.org/10.1115/1.2794191
  5. Fukushima, T., Homma, T., Harakawa, K., Sakata, N. and Azuma, T., 1988, 'Vortex Generation in Pulsatile Flow Through Arterial Bifurcation Models Including the Human Carotid Artery,' Journal of biomechanical engineering, Vol. 110, pp. 166-171 https://doi.org/10.1115/1.3108426
  6. Duncan, D. D., Bargeron, C. B., Borchardt, S. E., Deters, O. J., Gearhart, S. A., Mark, F. F. and Friedman, M.H., 1990, 'The Effect of Compliance on Wall Shear in Casts of a Human Aortic Bifurcation,' Journal of biomechanical engineering, Vol. 112, pp. 183-188 https://doi.org/10.1115/1.2891170
  7. Xu, X. Y., Collins, M. W. and Jones, C. J. H., 1992, 'Flow Studies in Canine Artery Bifurcations Using a Numerical Simulation Method,' Journal of biomechanical engineering, Vol. 114, pp. 504-511 https://doi.org/10.1115/1.2894102
  8. Rindt, C. C. M. and Steenhoven, A. A. V., 1996, 'Unsteady Flow in a Rigid 3-D Model of the Carotid Artery Bifurcation,' Journal of biomechanical engineering, Vol. 118, pp. 90-96 https://doi.org/10.1115/1.2795950
  9. He, X. and Ku, D. N., 1996, 'Pulsatile Flow in the Human Left Coronary Artery Bifurcation: Average Conditions,' Journal of biomechanical engineering, Vol. 118,pp. 74-82 https://doi.org/10.1115/1.2795948
  10. Nakamura, M. and Sawada, T., 1988, 'Numerical Study on the Flow of a Non-Newtonian Fluid Through an Axisymmetric Stenosis,' Journal of biomechanical engineering, Vol. 110, pp. 137-143 https://doi.org/10.1115/1.3108418
  11. Luo, X. Y. and Kuang, Z. B., 1992, 'Non-Newtinian Flow Patterns Associated with an Arterial Stenosis,' Journal of biomechanical engineering, Vol. 114, pp.512-514 https://doi.org/10.1115/1.2894103
  12. Mittal, R., Simmons, S. P. and Udaykumar, H. S., 2001, 'Application of Large-Eddy Simulation to the Study of Pulsatile Flow in a Modeled Arterial Steosis,' Journal of biomechanical engineering, Vol. 123, pp. 325-332 https://doi.org/10.1115/1.1385840AdditionalInformation
  13. Long, Q., Ku, X. Y., Ramnarine, K. V., Hoskins, P., 2001, 'Numerical Investigations of Physiologically Realistic Pulsatile Flow Through Arterial Stenosis,' Journal of Biomechanics, Vol. 34, pp. 1229-1242 https://doi.org/10.1016/S0021-9290(01)00100-2
  14. Varghese, S. S. and Frankel, S. H., 2003, 'Numerical Modeling of Pulsatile Turbulent Flow in Stenotic Vessels,' Journal of biomechanical engineering, Vol. 125, pp. 445-461 https://doi.org/10.1115/1.1589774
  15. Cho, Y. I., Back, L. H. and Crawford, D. W., 1985, 'Experimental Investigation of Branch Flow Ratio, Angel and Reynolds Number Effects on the Pressure and Flow Fields in Arterial Branch Models,' Journal of biomechanical engineering, Vol. 107, pp. 257-267 https://doi.org/10.1115/1.3138551
  16. Suh, S. H., Yoo, S. S., Kim Y. H. and Roh, H. W., 1996, 'A Study on the Pulsatile Flow Characteristics of Newtonian and Non-Newtonian Fluids in the Bifurcated Tubes,' the Korea society of mechanical engineers, Vol. 20, No. 11, pp. 3607-3619
  17. Issa, R. I., 1985, 'Solution of the Implicitly Discretised Fluid Flow Equations by Operator-Splitting,' Journal of Computational Physics, Vol. 62, pp. 40-65 https://doi.org/10.1016/0021-9991(86)90099-9
  18. Tang, D., Yang, C., Kobayashi, S., Zheng, J. and Vito, R. P., 2003, 'Effect of Stenosis Asymmetry on Blood Flow and Artery Compression: A Three-Dimensional Fluid-Structure Interaction Model,' Annals of Biomedical Engineering, Vol. 31, pp. 1182-1193 https://doi.org/10.1114/1.1615577
  19. Wootton, D. M. and Ku, D. N., 1999, 'Fluid Mechanics of Vascular Systems, Diseases and Thrombosis,' Annual Reviews of Biomedical Engineering, Vol. 1, pp. 299-329 https://doi.org/10.1146/annurev.bioeng.1.1.299
  20. Berger, S. A. and Jou, L-D., 2000, 'Flow in Stenotic Vessels,' Annual Review Fluid Mechanics, Vol. 32, pp. 347-382 https://doi.org/10.1146/annurev.fluid.32.1.347
  21. Gertz, S. D. and Roberts, W. C., 1990, 'Hemo-dynamic Shear Force in Rupture of Coronary Arterial Atherosclerotic Plaques,' American Journal of Cardiol., Vol. 66, pp. 1368-1372 https://doi.org/10.1016/0002-9149(90)91170-B