Alibi Verification and the PCR Method to Estimate the Source of Epidemic for a Few Notified Cases of S. sonnei

산발적으로 신고되는 세균성이질환자의 감염원 추정을 위한 알리바이 확인 및 PCR(Polymerase Chain Reaction) 검사

  • Koh, Dai-Ha (Department of Preventive Medicine, College of Medicine, Chonbuk National University) ;
  • Yoon, Chai-Hyun (Department of Preventive Medicine, Graduate School of Public Health, Seoul National University) ;
  • Lee, Sin-Jae (Gangseogu Health Center, Seoul)
  • 고대하 (전북대학교 의과대학 예방의학교실) ;
  • 윤채현 (서울대학교 보건대학원 예방의학교실) ;
  • 이신재 (서울특별시 강서구 보건소)
  • Published : 2005.12.01

Abstract

Objectives : A few culture-confirmed cases of S. sonnei have been notified from Korean hospitals. The source of epidemic can't be firmly determined in such cases because of the rarity of this illness in the local communities and the timing of the outbreaks. The objective of this study is to estimate the source of epidemic by investigating the patients' lifestyles. Methods : Alibi verification was used to access the presumed source of the epidemic. PCR (Polymerase Chain Reaction) was used to rapidly detect the genes of Shigella in water specimens. Results : The common lifestyle trait among the Shigella infected patients was connected with Mt. Martyr in J city, Korea. The first patient's son had gone on a pilgrimage to Mt. Martyr with 41 friends and he had only eaten rice cakes on April 5th; the second patients had visited Mt. Martyr with their mother for a picnic on April 12th; the third patient had visited Mt. Martyr with 22 friends for a pilgrimage and the patient had only drunk holy water on April 13th. Therefore, the holy water of Mt. Martyr was reckoned to be the source of the epidemic. PCR detected the genes of Shigella two days before the S. sonnei was confirmed. Conclusion : The patients' lifestyles for 7 days before the onset of symptoms should be determined in terms of time, place and contacted people to find the source of infection when cases with food poisoning are seen in the hospital setting.

Keywords

References

  1. Liu C. The battle against SARS: A Chinese story. Aust Health Rev 2003; 26(3): 3-13 https://doi.org/10.1071/AH030003
  2. WHO, WHO issues consensus document on the epidemiology of SARS. Wkly Epidemiol Rec 2003; 78(43): 373-375
  3. CDMR. 세균성이질발생-제주도. volume 11 number 7 July 2000
  4. KCDC. Communicable Disease Stastistical Book. 2003: 8-171
  5. Lee YJ, Hwang UK, Kim JS, Kim JY, Koo JS, Lee BK, Kang JW. Epidemiologic investigation on sporadic cccurrence of shigellosis in a subcounty of Cheongwon county in Chungbuk province in 2003, J Prev Med Public Health 2005; 38(2): 182-188 (Korean)
  6. 국립보건원. 전염병 보고 및 정보관리지침, 2003
  7. 국립보건원. 수인성/식품매개성 전염병 . 식중독조사 지침, 2003
  8. Goodman RA, Bauman CF, Gregg MB, Videtto JF, Stroup DF, Chalmers NP. Epidemiologic field investigations by the centers for disease control and epidemic intelligence service, 1946- 87. Public Health Rep 1990; 105(6): 604-610
  9. Barbara B. A guide to physical examination and history taking. 4th ed. J.B. Lippincott Company; 1987; 1
  10. Senthil N, Paul P. Food poisoning. emedicine instant access to the minds of medicine; Available from URL: http://www.emedicine.com/med/topic807htm
  11. Guerrant RL, Van GT, Steiner TS, Thielman NM, Slutsker L, Tauxe RV, Hennessy T, Griffin PM, DuPont H, Sack RB, Tarr P, Neill M, Nachamkin I, Reller LB, Osterholm MT, Bennish ML, Pickering LK; Infectious diseases society of America. practice guidelines for the management of infectious diarrhea. Clin Infect Dis 2001; 32(3): 331-351 https://doi.org/10.1086/318514
  12. Dupont HL. Practice parameters committee of the American college of gastro-enterology. guidelines on acute infectious diarrhea in adults. Am J Gastroenterol 1997; 92: 1962
  13. Thielman NM, Guerrant RL. Clinical practice. Acute infectious diarrhea. N Engl J Med 2004; 350(1): 38-47 https://doi.org/10.1056/NEJMcp031534
  14. Richard E Frye, M AKram Tramer. Gastroenteritis, bacterial. emedicine instant access to the minds of medicine; available from URL:http:// www.emedicine.com/med/topic 855htm
  15. Lee DW, Cho KW, Lee KS, Lee SJ. Family practise residents' diagnostic and therapeutic behaviors to acute diarrheal patients. J Korean Acad Fam Med. 2003; 24: 1104-1109 (Korean)
  16. National Institute of Health. Criterion to report of communicable disease and management of information 2003; 15-18 (Korean)
  17. 이병철. 경영정보시스템. 법경사. 2000; 352