Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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Epidemiologic Investigation on Sporadic Occurrence of Shigellosis in a Subcounty of Cheongwon County in Chungbuk Province in 2003

청원군 일개 면에서 산발적으로 신고한 세균성이질 집단 발병 역학조사

  • Lee, Yong-Jae (Division of Epidemic Intelligence Service, Korea Center for Disease Control and Prevention) ;
  • Hwang, Ue-Kyoung (Department of Family Medicine, Seoul Paik Hospital, Inje University College of Medicine) ;
  • Kim, Jong-Suk (Department of Microbiology, Chungbuk Institute of Health and Environment Research) ;
  • Kim, Jun-Young (Division of Enteric Infections, Department of Bacteriology, National Institute of Health) ;
  • Lee, Bok-Kwon (Division of Enteric Infections, Department of Bacteriology, National Institute of Health, Korea) ;
  • Koo, Ja-Seol (Division of Bioterrorism Preparedness and Response, Korea Center for Disease Control and Prevention) ;
  • Kang, Jong-Won (Department of Preventive Medicine, College of Medicine, Chungbuk National University)
  • 이용제 (질병관리본부 역학조사과) ;
  • 황의경 (인제대학교 의과대학 서울 백병원 가정의학교실) ;
  • 김종숙 (충청북도 보건환경연구원) ;
  • 김준영 (국립보건연구원 장내세균과) ;
  • 이복권 (국립보건연구원 장내세균과) ;
  • 구자설 (질병관리본부 생물테러대응과) ;
  • 강종원 (충북대학교 의과대학 예방의학교실)
  • Published : 2005.06.01
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Abstract

Objectives: This study was undertaken to investigate the source of infection and mode of transmission of shigellosis, which occurred sporadically among residents and students in a subcounty of Cheongwon county, Chungbuk province, Korea, from June 4 to July 3 2003. Methods: 692 subjects completed a questionnaire and provided a swab for microbiological examinations,and 7 environmental specimens were examined for bacterial organisms. PFGE (pulsed-field gel electrophoresis) and fingerprinting were performed to find the genetic relationship among the temporally associated sporadic isolates. Results: A total of 29 patients had symptoms consistent with the case definition, with 13 confirmed and 16 suspected cases. The frequency of diarrhea was 6 times or more a day (80.8%), with a duration of 1 to 4 days (88.5%) in most cases. The most common symptoms accompanying the diarrhea were fever (80.9%) followed by abdominal pain (76.9%), headache (65.4%), chill (61.5%), vomiting (46.2%) and tenesmus (15.4%). The epidemic curve was characteristic of a person-to-person transmission. The PFGE and fingerprinting demonstrated identical or similar DNA patterns among the 3 Shigella sonnei isolates (A51, A53 and A61 types) found in this outbreak. Conclusion: A genetically identical strain of S. sonnei was estimated to be the cause of this outbreak, and the mode of transmission was most likely person-to-person.

Keywords

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