Clinical evaluation of full mouth disinfection therapy

Full mouth disinfection therapy의 단기간 임상 효과 연구

  • Cho, Ik-Hyun (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration) ;
  • Jung, Ui-Won (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration) ;
  • Cha, Jeong-Heon (Department of Oral biology, College of Dentistry, Yonsei University) ;
  • Kim, Joong-Su (Genome Research Center, Korea Research Institude of Bioscience & Biotechnology) ;
  • Lee, Dae-Sil (Genome Research Center, Korea Research Institude of Bioscience & Biotechnology) ;
  • Kim, Chang-Seong (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration, Brain Korea 21 project for Medical Science) ;
  • Kim, Chong-Kwan (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration, Brain Korea 21 project for Medical Science) ;
  • Choi, Seong-Ho (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration, Brain Korea 21 project for Medical Science)
  • 조익현 (연세대학교 치과대학 치주과학교실, 치주 조직 재생연구소) ;
  • 정의원 (연세대학교 치과대학 치주과학교실, 치주 조직 재생연구소) ;
  • 차정헌 (연세대학교 치과대학 구강생물학교실) ;
  • 김중수 (한국 생명공학 연구원) ;
  • 이대실 (한국 생명공학 연구원) ;
  • 김창성 (연세대학교 치과대학 치주과학교실, 치주 조직 재생연구소, BK21 의과학사업단) ;
  • 김종관 (연세대학교 치과대학 치주과학교실, 치주 조직 재생연구소, BK21 의과학사업단) ;
  • 최성호 (연세대학교 치과대학 치주과학교실, 치주 조직 재생연구소, BK21 의과학사업단)
  • Published : 2005.09.30

Abstract

The aim of this study is to determine whether full-mouth disinfection therapy(FMT) in our clinical setting would show better improvement of clinical parameters than partial mouth disinfection therapy(PMT) in chronic periodontitis and aggressive periodontitis patients. Among 12 patients, 6 were treated FMT and other 6 were treated PMT. Clinical parameters were calculated 3 months and 6 months after initial therapy. 1. There were no statistically significant differences between FMT and PMT in the reduction rate of bleeding on probing after 3 months, 6 months 2. Initial probing depth was 4-6mm, the mean probing depth after 3 months was 2.2mm vs 2.5mm(FMT vs PMT), after 6 months was 2.4mm vs 2.8mm. This was significantly lower in the FMT groups. 3. Initial probing depth was ${\geqq}$ 7mm, the reduction rate of mean probing depth during first 3 months was 4.8mm vs 4.1mm(FMT vs PMT), and 3 to 6 months was 0.5mm vs 0.3mm. This was significantly larger in the FMT groups. 4. Initial probing depth was 4-6mm, the mean clinical attachment level after 3 months was 2.3mm vs 2.7mm(FMT vs PMT), after 6 months was 2.7mm vs 3.0mm. This was significantly lower in the FMT groups. 5. Initial probing depth was ${\geqq}$ 7mm, the reduction rate of mean probing depth during first 3 months was 4.0mm vs 3.0mm(FMT vs PMT), and 3 to 6 months was 0mm vs -0.1mm. This was significantly larger in the FMT groups. Although the results provided us with succeccful clinical improvement in aggressive periodontitis, further research is needed to prove its additional benefit in the treatment of chronic periodontitis

Keywords

References

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