The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
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Fine Needle Aspiration Cytology of Mucinous Cystic Carcinoma of the Pancreas - A Case Report -

췌장의 점액 낭샘암종의 세침흡인 세포소견 -1예 보고-

  • Lee,, Kyung-Ji (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea) ;
  • Lee, Kyo-Young (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea) ;
  • Kang, Chang-Suk (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea) ;
  • Shim, Sang-In (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea) ;
  • Lee, Ah-Won (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea)
  • 이경지 (가톨릭대학교 의과대학 임상병리학교실) ;
  • 이교영 (가톨릭대학교 의과대학 임상병리학교실) ;
  • 강창석 (가톨릭대학교 의과대학 임상병리학교실) ;
  • 심상인 (가톨릭대학교 의과대학 임상병리학교실) ;
  • 이아원 (가톨릭대학교 의과대학 임상병리학교실)
  • Published : 2005.11.30
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Abstract

Mucious cystic neoplasm of pancreas is a cystic neoplasm composed of columnar, mucin-producing epithelium and is supported by ovarian-type stroma. The key to the cytologic evaluation of pancreatic cystic lesions is to recognize the cytologic components as being diagnostic of a mucin-producing cystic neoplasm, as all of these neoplasms need to be resected. We report the use of fine needle aspiration cytology in the diagnosis of an invasive mucinous cystic carcinoma confirmed by partial pancreatectomy. The cytologic specimen showed a abundant mucin background and sheets or papillae of neoplastic cells. There are mucin-containing columnar cells that show a variable degree of cytologic atypia.

Keywords

References

  1. Compagno J, Oertel J. Mucinous cystic neoplasia of the pancreas with overt and latent malignancy (cystadenocarcinoma and cystadenoma): a clinicopathologic study of 41 cases. Am J Clin Pathol 1978;69:573-80 https://doi.org/10.1093/ajcp/69.6.573
  2. Thompson LD, Becker RC, Przygodzki RM, Adair CF, Heffess CS. Mucinous cystic neoplasm (mucinous cystadenocarcinoma of low-grade malignant potential) of the pancreas; a clinicopathologic study of 130 cases. Am J Surg Pathol 1999; 23:1-16 https://doi.org/10.1097/00000478-199901000-00001
  3. Zamboni G, Longnecker DS, Kloppel G, Adler G, Hruban RH. Mucinous cystic neoplasms of the pancreas. In : Hamilton R, Aaltonen LA. Pathology and Genetics of Tumor of the Digestive System. Lyon, France: IARC Press, 2000:234-6
  4. Sohn JH, Kim KM, Chae SW, et al. Prevalence and clinicopathologic features of mucinous cystic tumor and intraductal papillary mucinous tumor of pancreas in Korea. Korean J Pathol 2003;37:270-8
  5. Yeh MM, Tang LH, Wang S, Robert ME, Zheng W, Jain D. Inhibin expression in ovarian-type stroma in mucinous cystic neoplasms of the pancreas. Appl Immunohistochem Mol Morphol 2004;12:148-52
  6. Centeno BA. Role of cytology in the diagnosis of cystic and intraductal papillary mucinous neoplasms. Gastrointest Endoscopy Clin N Am 2002;12:697-708 https://doi.org/10.1016/S1052-5157(02)00024-7
  7. Recine M, Kaw M, Evans DB, Krishnamurthy S. Fine-needle aspiration cytology of mucinous tumors of the pancreas. Cancer(Cancer Cytopathol) 2004;102:92-9 https://doi.org/10.1002/cncr.20052
  8. Stelow E, Stanley MW, Bardales RH, et al. Intraductal papillary-mucinous neoplasm of the pancreas: The findings and limitations of cytologic samples obtained by endoscopic ultrasound-guided fine-needle aspiration. Am J Clin Pathol 2003;120:398-404 https://doi.org/10.1309/CEPK542W38852LP8
  9. Layfield LJ, Cramer H. Fine-needle aspiration cytology of intraductal papillary-mucinous tumors: A retrospective analysis. Diagn Cytopathol 2005;32:16-20 https://doi.org/10.1002/dc.20149