Molecular & Cellular Toxicology

The Korean Society of Toxicogenomics and Toxicoproteomics (대한독성유전 단백체학회)
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Enhanced Biodegradation of Environmental Allergen by a vgb-containing Burkholderia cepacia

  • Kim, Mi-Sun (Korea Research Institute of Bioscience and Biotechnology) ;
  • Yoon, Suk-Ran (Korea Research Institute of Bioscience and Biotechnology) ;
  • Jun, Woo-Jin (Department of Food and Nutrition, College of Human Ecology, Chonnam National University) ;
  • Park, So-Young (Department of Cell and Molecular Biology, Feinberg School of Medicine, and Institute for Neuroscience, Northwestern University) ;
  • Yang, Young (Department of Biological Science, College of Science, Sookmyung Women's University) ;
  • Shim, Sang-In (Division of Plant Resources and Environment, Gyeongsang National University) ;
  • Hwang, Kwang-Woo (School of Pharmacy, Choong-Ang University) ;
  • Chung, Jin-Woong (Korea Research Institute of Bioscience and Biotechnology)
  • Published : 2005.12.30
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Abstract

Using genetic engineering, the Vitreoscilla (bacterial) hemoglobin gene (vgb) was integrated stably into the chromosomes of and Burkholderia cepacia. Similar to previous results, the wild type VHb improved growth for Burkholderia cepacia and degradation of benzoic acid under both normal and low aeration conditions. The stable expression of VHb enhanced these parameters. The results demonstrate the possibility that the positive effects provided by VHb may be augmented by protein engineering.

Keywords

References

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