한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제22권1호
  • /
  • Pages.26-30
  • /
  • 2005
  • /
  • 1598-298X(pISSN)
  • /
  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

대전지역 아토피성 피부염 이환견의 양성항원 분포

Prevalence of Causative Allergens on Canine Atopic Dermatitis in Daejeon Area

  • 송근호 (충남대학교 수의과대학 수의내과학교실) ;
  • 이정연 (일본 오비히로 축산대학) ;
  • 류건주 (충남대학교 수의과대학 수의내과학교실) ;
  • 이상은 (충남대학교 수의과대학 수의내과학교실) ;
  • 박성준 (충남대학교 수의과대학 수의내과학교실) ;
  • 김덕환 (충남대학교 수의과대학 수의내과학교실)
  • Song Kun-ho (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Lee Jung-youn (Obihiro University of Agriculture and Veterinary Medicine) ;
  • Liu Jianzhu (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Lee Sang-eun (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Park Seong-jun (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Kim Duck-hwan (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University)
  • 발행 : 2005.03.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

The purpose of this study is to investigate the prevalent allergens causing canine atopic dermatitis in Daejeon area. Twenty two dogs were diagnosed with atopic dermatitis by an using intradermal skin test (IDST). Allergens used for the IDST included 33 allergen extracts from nine allergen groups: house dust mites (HDM), house dust, moulds, trees, weeds, grasses, insects/fleas, epithelia and others. The 22 purebred dogs with atopic dermatitis enrolled in this study included Shi-tzus (10/22, 45.5%), Yorkshire terriers (5/22, 22.7%), Miniature pinschers (4/22, 18.2%), Pugs (2/ 22, 9.1 %) and Cocker spaniels (1/22, 4.5%). The age of onset of atopic dermatitis ranged from 5 months to 5 years old (median: 1.79 years). The males (12/22, 54.5%) and females (10/22, 45.5%) were almost equal. The number of positive reactions to allergens recorded in each dog with atopic dermatitis was 3 (9/22, 40.9%), 2 (8/22, 36.4%), 1 (3/ 22, 13.6%) and 4 (2/22, 9.1 %), respectively. The most common positive allergen reaction was HDM (52.6%). The other positive allergen reactions recorded were from house dust (17.5%), insects/fleas (15.8%), trees (5.3%), moulds (3.5%), kapok (3.5%), silk (3.5%), epithelia (1.8%), weeds (0%) and grasses (0%), respectively. Positive reactions recorded to Dermatophagoides farinae and D. pteronyssinus were in 53.3% and 46.7%, respectively. The IDST results demonstrate that the most common causative allergens in canine atopic dermatitis in Daejeon area were HDM.

키워드

참고문헌

  1. August JR. The intradermal skin test as a diagnostic aid for canine atopic disease. J Am Aanim Hosp Assoc 1982; 18: 164-171
  2. Barker JNSN, MacDonald DM. Epidermal class II human lymphocyte antigen expression in atopic dermatitis: A comparison with experimental allergic contact dermatitis. J Am Acad Dermatol 1987; 16: 1175-1179 https://doi.org/10.1016/S0190-9622(87)70153-4
  3. Bond R, Thorogood, SC, Lloyd DH. Evaluation of two enzyme-linked immunosorbent assay for the diagnosis of canine atopy. Vet Rec 1994; 135: 130-133 https://doi.org/10.1136/vr.135.6.130
  4. Carlotti DN, Costargent F. Analysis of positive skin tests in 449 dogs with allergic dermatitis. Prak Med Chir An Cie 1992; 27: 53-69
  5. Conder EC, Lessard P. Effect of hyposensitization with irrelevant antigens on subsequent allergy test results in normal dogs. Vet Dermatol 1992; 3: 209-214 https://doi.org/10.1111/j.1365-3164.1992.tb00175.x
  6. Conder EC, Lessard P. Comparison of intradermal allergy test and enzyme-linked immunosorbent assay in dogs with allergic skin disease. J Am Vet Med Assoc 1993; 202: 739-743
  7. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Dermatol Venereol (Stockh) 1980; 92: 44-47
  8. Masuda K, Sakaguchi M, Fujiwara S, Kurata K, yamashida K, Odagiri T. Positive reactions to common allergens in 42 atopic dogs in Japan. Vet Immuno Immunopathol 2000; 73: 193-204 https://doi.org/10.1016/S0165-2427(99)00166-X
  9. Medleau L, Hnilica KA. Small animal dermatology. 1st ed. Philadelphia: WB Saunders. 2001: 118-120
  10. Miller WH, Scott DW, Scarlett JM. Evaluation of allergy screening test for use in atopic dogs, J Am Vet Med Assoc 1992; 200: 931-935
  11. Mueller RS, Bettenay SV. Long-term immunotherapy of 146 dogs with atopic dermatitis-a retrospective study. Aust Vet Pract 1996; 26: 128-132
  12. Nesbitt GH. Canine allergic inhalant dermatitis: a review of 230 cases. J Am Vet Med Assoc 1978; 172: 55-60
  13. Nuttal TJ, Thoday KL, Van den Broek AHM. Retrospective survey of allergen immunotherapy in canine atopy. Vet Rec 1998; 143: 139-142 https://doi.org/10.1136/vr.143.5.139
  14. Rajka G, Langeland T. Grading of severity of atopic dermatitis. Acta derm Venerol 1980; 144: 13-14
  15. Reedy LM, Miller WH, Willemse T. Allergic skin diseases of dogs and cats. 2nd ed. Philadelphia: WB Saunders. 1999: 44-45
  16. Schick RO, Fadok VA. Response of atopic dogs to regional allergens: 268 cases (1981-1984). J Am Vet Med Assoc 1986; 189: 1493-1496
  17. Scott DW, Miller WH, Griffin CE. Skin immune system and allergic skin disease. In: Muller & Kirk's Small Animal Dermatology, 6th ed. Philadelhia: Saunders. 2001: 543-666
  18. Sture GH, Halliwell REW, Thody KL. Canine atopic disease: the prevalence of positive intradermal skin tests at two sites in the north and south of Great Britain. Vet Immuno Immunopathol 1995; 44: 293-308 https://doi.org/10.1016/0165-2427(94)05306-D
  19. Youn HY, Kang HS, Bhang DH, Kim MK, Hwang CY, Han HR. Allergens causing atopic diseases in canine. J Vet Sci 2002; 3: 335-341
  20. Willemse T. Atopic skin disease: a review and a reconisideration of diagnostic criteria. J Small Anim Pract 1986; 27: 771-778 https://doi.org/10.1111/j.1748-5827.1986.tb02119.x
  21. Zur G, White SD, Ihrke PJ, Kass PH, Toebe N. Canine atopic dermatitis: a retrospective study of 169 cases examined at the University of California, Davis, 1992-1998, part III. Response to hyposensitization. Vet Dermatol 2002; 13: 103-111