Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Scintigraphic Evaluation of Dogs with Experimentally Transected Cranial Cruciate Ligaments Treated Using Tibial Plateau Leveling Osteotomy

실험적으로 전십자 인대를 단열한 개에서 TPLO의 핵의학적 평가

  • Lee Jae yeong (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Kim Joong-hyun (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Lee Won guk (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Kang Seong soo (College of Veterinary Medicine and Biotechnology Research Institute, Chonnam National University) ;
  • Bae Chun sik (College of Veterinary Medicine and Biotechnology Research Institute, Chonnam National University) ;
  • Choi Seok hwa (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University)
  • 이재영 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 김중현 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 이원국 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 강성수 (전남대학교 수의과대학 및 생물공학연구소) ;
  • 배춘식 (전남대학교 수의과대학 및 생물공학연구소) ;
  • 최석화 (충북대학교 수의과대학 및 동물의학연구소)
  • Published : 2005.03.01
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Abstract

This study was performed to assess therapeutic effect of the tibial plateau leveling osteotomy (TPLO) in dogs with experimentally transected cranial cruciate ligaments (CrCL). Nine healthy adult Beagle dogs were transected left CrCL under general anesthesia. The dogs were assigned to TPLO and non-TPLO control groups. The TPLO procedures for correcting the CrCL rupture in the left stifle of dogs were performed under sterile conditions. Before TPLO procedures, all dogs were screened by orthopedic and radiographic examinations. Dogs were lameness free for the previous three months, and when examined at the walk and trot on a hard surface, in a straight line and on a circle. Lateral and craniocaudal radiographs were done to confirm the soundness of the both knee joint in dogs and not detectable lesions were diagnosed. The dogs were intravenously injected with a 10 mci/kg of 99mTechnetium-methylene diphosphonate (99mTc-MDP) under general anesthesia. Scintigraphs were obtained using a large field of view gamma camera equipped a parallel-hole, low-energy about 3 hours after intravenous injection of 99mTc-MDP. Before CrCL transection and 4, 8, and 12 weeks after the procedures, scintigraphy were conducted. Bone uptake of the left stifle joint increased after the procedures in all dogs. When the bone uptake from the TPLO procedure was compared with that of the control, there was a significant difference (p < 0.05). At 12 weeks after the TPLO procedure, the dogs showed normal anatomical posture and gait. It is concluded that TPLO procedure was effective in reconstruct of the stifle joint in dogs with CrCL rupture.

Keywords

References

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