한국전문물리치료학회지 (Physical Therapy Korea)
- 제12권1호
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- Pages.80-90
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- 2005
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- 1225-8962(pISSN)
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- 2287-982X(eISSN)
맥동성 초음파가 흰쥐 창상치유에 미치는 조직학적 변화
The Histological Observation of the Effects of Pulsed Ultrasound on Wound Healing of Rats
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김계엽
(동신대학교 물리치료학과) ;
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김태열
(동신대학교 물리치료학과) ;
- 나수영 (동신대학교 물리치료학과) ;
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김경윤
(동신대학교 물리치료학과) ;
- 김기도 (동신대학교 물리치료학과) ;
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김종만
(서남대학교 물리치료학과)
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Kim, Gye-Yeop
(Dept. of Physical Therapy, Dongshin University) ;
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Kim, Tae-Youl
(Dept. of Physical Therapy, Dongshin University) ;
- Na, Soo-Young (Dept. of Physical Therapy, Dongshin University) ;
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Kim, Kyung-Yoon
(Dept. of Physical Therapy, Dongshin University) ;
- Kim, Gi-Do (Dept. of Physical Therapy, Dongshin University) ;
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Kim, Jong-Man
(Dept. of Physical Therapy, Seonam University)
- 발행 : 2005.02.19
초록
The purpose of this study was to evaluate the effects of pulsed ultrasound on wound healing and observe during the wound healing process the distribution of mast cells according to histopathologic findings. Eighty Sprague Dawley rats which were divided into 4 groups received full thickness skin wounds on the back. Each of the 5 animals was sacrificed immediately and then sacrificed again 1, 3, 6, and 12 days after injury. Specimens from the wounds were removed during healing and routinely processed with a hematoxylin-eosin stain and a toluidine blue stain. The authors then observed the distribution of mast cells under a light microscope. The results of this study were as follows: The rate of wound healing and the length of the wounds of the pulsed ultrasound group II was significantly faster than group I on day 6 and day 12 (p<.001). Group III showed the most significant effect after12 days (p<.001). Group IV also showed a significant effect at 12 days (p<.01). A low-intensity ultrasound .5