Comparative efficacy of anticoccidical drugs in coccidiosis of broiler chicks

  • Ejaz Sohail (Biosafety Research institute and Department of Pathology, College of Veterinary Medicine, Chonbuk National University) ;
  • Chekarova Irina (Biosafety Research institute and Department of Pathology, College of Veterinary Medicine, Chonbuk National University) ;
  • Yoon Hyun-Sang (Biosafety Research institute and Department of Pathology, College of Veterinary Medicine, Chonbuk National University) ;
  • Lee Seung-Yeon (Biosafety Research institute and Department of Pathology, College of Veterinary Medicine, Chonbuk National University) ;
  • Oh Myong-Ho (Biosafety Research institute and Department of Pathology, College of Veterinary Medicine, Chonbuk National University) ;
  • Berzina Dace (Biosafety Research institute and Department of Pathology, College of Veterinary Medicine, Chonbuk National University) ;
  • Kwon Hyuk-Nyun (Biosafety Research institute and Department of Pathology, College of Veterinary Medicine, Chonbuk National University) ;
  • Kim Bum-Seok (Department of Pathology, College of Veterinary Medicine, University of Tennessee) ;
  • Lim Chae-Woong (Biosafety Research institute and Department of Pathology, College of Veterinary Medicine, Chonbuk National University)
  • 발행 : 2005.12.01

초록

Coccidiosis of domestic fowl is a parasitic disease that infects poultry drastically and can cost the pastured poultry producer much in the course of a year. Two hundred forty, day-old-broiler chicks were purchased and were randomly divided in eight groups, containing thirty birds in each group. Decoquinate $6\%$, maduramicin ammonium $2\%$, monensin sodium $13.2\%$, salinomycin sodium $12\%$, a live attenuated vaccine, and trivalent live attenuated vaccine, was provided to the day chicks of six groups, respectively. The chicks of last two groups served as infected non-medicated and uninfected non-medicated, respectively. Feed consumption, weight gain, feed conversion ratio, mortality and oocyst count per gram feces were recorded during the conduction of the experiment. Among treated groups, performance of salinomycin group was significantly better (p<0.05) in all aspects. Salinomycin acts against the sporozoites, trophozoites and first generation schizonts and is highly effective against the economically important species of Eimeria. The present study confirms that use of salinomycin, as an anticoccidial, is a drug of choice.

키워드

참고문헌

  1. Shirley MW. 1995. Eimeria spp. and strains of chickens. In: Eckert J, Braun R, Shirley MW, et al. Guidelines on techniques in coccidiosis research. European Commission, Directorate General XII, Science Research and Development, Agriculture Biotechnology, L-2820 Luxemburg: 1-34
  2. Callow LL. 1984. Eimeria in domestic fowls. In: Callow LL. (Ed.), Animal Health in Australia, Vol. 5. Australian Publishing Service, Canberra: 35-47
  3. Fernandez S, Costa AC, Katsuyama AM, et al. 2003. A survey of the inter-and intra-specific RAPD markers of Eimeria spp. of the domestic fowl and the development of reliable diagnostic tools. Parasitol Res 89(6):437-445
  4. Jorgensen WK, Stewart NP, Jeston PJ, et al. 1997. Isolation and pathogenicity of Australian strains of Eimeria praecox and Eimeria mitis. Aust Vet J 75: 592-595 https://doi.org/10.1111/j.1751-0813.1997.tb14201.x
  5. McDougald LR, Reid WM. 1997. In: Calnek BW, Barnes HJ, Beard CW, et al (Eds.), Diseases of Poultry, Iowa State University Press, Ames, IA, pp. 865-883
  6. Fernando AM. 1973. Eimeria: Infections of the intestine, In Long PL (ed.), Coccidiosis of man and domestic animals. CRC Press, Inc., Boca Raton, Fla: 63-75
  7. Braunius WW. 1988. Epidemiology of Eimeria spp. in broiler chicks as influenced by anticoccidial agents. Tijdschrt Diergeneeskd 113:123-131
  8. Magner BR. 1991. Anticoccidials. In: Brander GC, Pugh DM, Bywater RJ, et al. 1991. Veterinary Applied Pharmacology and Therapeutics, 5th Ed. ELBS, Bailliere Tindall, London: 549-563
  9. Williams RB. 1998. Epidemiological aspects of the use of live anticoccidial vaccines for chickens. Int J Parasitol 28:1089-1098 https://doi.org/10.1016/S0020-7519(98)00066-6
  10. Allen PC, Fetterer RH. 2002. Recent advances in biology and immunobiology of Eimeria species and diagnosis and control of infection with these coccidian parasites of poultry. Clin Microbiol Rev 15:58-65 https://doi.org/10.1128/CMR.15.1.58-65.2002
  11. Norman DL. 1985. Veterinary Protozoology. Iowa State University Press, USA
  12. Urquhart GM. Armour J, Duncan JL, et al. 1996. Veterinary parasitology. Blackwell Science. UK
  13. Steel RGD, Torrie JH. 1980. Principles and procedures of statistics. McGraw Hill Book Co Inc. New York: 137-171
  14. Chapman HD. 1997. Biochemical, genetic and applied aspects of drug resistance in Eimeria parasites of the fowl. Avian Pathol 26:221-244 https://doi.org/10.1080/03079459708419208
  15. Williams RB. 1992. The development, efficacy and epidemiological aspects of ParacoxTM, a new coccidiosis vaccine for chickens. Harefield: PitmanMoore Europe
  16. Williams RB, Gobbi L. 2002. Comparison of an attenuated anticoccidial vaccine and an anticoccidial drug programme in commercial broiler chickens in Italy. Avian Pathol 31(3):253-265 https://doi.org/10.1080/03079450220136567
  17. Chapman HD. Cherry TE, Danforth HD, et al. 2002. Sustainable coccidiosis control in poultry production: the role of live vaccines. Int J Parasitol 32(5):617-29 https://doi.org/10.1016/S0020-7519(01)00362-9
  18. Vermeulen AN, Schaap DC, Schetters TP. 2001. Control of coccidiosis in chickens by vaccination. Vet Parasitol 100(1-2):13-20 https://doi.org/10.1016/S0304-4017(01)00479-4
  19. Conway DP, Mathis GF, Lang M. 2002. The use of diclazuril in extended withdrawal anticoccidial programs: 2. Immunity to Eimeria tenella challenge after drug withdrawal. Poult Sci 81(3):353-355 https://doi.org/10.1093/ps/81.3.353
  20. Conway DP, Mathis GF, Johnson J, et al. 2001. Efficacy of diclazuril in comparison with chemical and ionophorous anticoccidials against Eimeria spp. in broiler chickens in floor pens. Poult Sci 80(4):426-430 https://doi.org/10.1093/ps/80.4.426
  21. Hooge DM, Cummings KR, McNau-ghton JL. 1999. Evaluation of sodium bicarbonate, chloride, or sulfate with a coccidiostat in corn-soy or corn-soy-meat diets for broiler chickens. Poult Sci 78(9): 1300-1306 https://doi.org/10.1093/ps/78.9.1300
  22. Augustine PC, Danforth HD. 1999. Influence of betaine and salinomycin on intestinal absorption of methionine and glucose and on the ultrastructure of intestinal cells and parasite developmental stages in chicks infected with Eimeria acervulina. Avian Dis 43(1):89-97 https://doi.org/10.2307/1592766
  23. Jaramillo M, Ruiz H, Silva L. 1998. Comparative evaluation of triamcinolone in coccidiosis control in fattening chickens. Acta Cient Venez 49(1) : 62-67.
  24. Gray SJ, Ward TL, Southern LL, et al. 1998. Interactive effects of sodium bentonite and coccidiosis with monensin or salinomycin in chicks. Poult Sci 77(4):600-604 https://doi.org/10.1093/ps/77.4.600
  25. Allen PC. Danforth HD, Augustine PC. 1998. Dietary modulation of avian coccidiosis. Int J Parasitol 28(7):131-140
  26. Conway DP, Dayton AD, McKenzie ME. 1999. Comparative testing of anticoccidials in broiler chickens: the role of coccidial lesion scores. Poult Sci 78(4):529-535 https://doi.org/10.1093/ps/78.4.529
  27. Daugschies A, Gasslein U, Rommel M. 1998. Comparative efficacy of anticoccidials under the conditions of commercial broiler production and in battery trials. Vet Parasitol 76(3):163-171 https://doi.org/10.1016/S0304-4017(97)00203-3
  28. McAllister TA, Annett CB, Olson ME, et al. 1996. Effect of salinomycin on giardiasis and coccidiosis in growing lambs. J Anim Sci 74(12):2896-2903
  29. Leblanc D, Morin A, Daigneault J. 1993. Comparative effect of salinomycin and monensin on Streptococcus bovis strain ATCC 9809. Microbios 76(306):41-45
  30. Daugschies A, Gasslein U, Rommel M. 1998. Comparative efficacy of anticoccidials under the conditions of commercial broiler production and in battery trials. Vet Parasitol 76(3):163-171 https://doi.org/10.1016/S0304-4017(97)00203-3