Surgical Margins for Excision of Dermatofibrosarcoma Protuberans

융기성 피부섬유육종의 외과적 절제연

  • Bae, Yong Chan (Department of Plastic and Reconstructive Surgery, Pusan National University, Busan) ;
  • Moon, Jae Sul (Department of Plastic and Reconstructive Surgery, Pusan National University, Busan) ;
  • Nam, Su Bong (Department of Plastic and Reconstructive Surgery, Pusan National University, Busan)
  • 배용찬 (부산대학교 의과대학 성형외과학교실) ;
  • 문재술 (부산대학교 의과대학 성형외과학교실) ;
  • 남수봉 (부산대학교 의과대학 성형외과학교실)
  • Received : 2005.01.03
  • Published : 2005.07.10

Abstract

Dematofibrosarcoma protuberans(DFSP) is a moderate-degree malignant tumor with high recurrence rate and low metastasis rate, from soft tissue. Principle of treatment is wide excision or Mohs micrographic surgery(MMS). Although wide excision has been performed with surgical margins of 2-5 cm until nowadays, there are problems of preservation of surrounding normal tissue. Therefore the authors tried to identify desirable surgical margins and operative method. From January 1999 to April 2003, 12 patients with DFSP were operated. We applied different surgical margins and operative methods according to the location of lesions. On the face, we performed MMS with surgical margin of 3-4 mm in 2 cases although there are problems of operation time and expense. But on the extremities and trunk, we performed authors' method to begin excising with surgical margins of 1 cm and excise extensively with MMS by 1 cm in 4 cases after April, 2001 although we had performed wide excision with surgical margin of 3 cm in 6 cases before. There was no recurrence or metastasis in the follow-up period. So we think that author's method is effective in surgical excision of DFSP

Keywords

References

  1. Pack GT, Tabah EJ: Dermatofibrosarcoma protuberans. Arch Surg 62: 391, 1951 https://doi.org/10.1001/archsurg.1951.01250030397008
  2. Taylor HB, Helwig EB: Dermatofibrosarcoma protuberans: a study of 115 cases. Cancer 15: 717, 1962 https://doi.org/10.1002/1097-0142(196207/08)15:4<717::AID-CNCR2820150405>3.0.CO;2-2
  3. Bendix HK, Myhre JO, Kaae S: Dermatofibrosarcoma protuberans: A clinicopathological study of nineteen cases and review of world literature. Scan J Plast Surg Hand Surg 17: 247, 1983 https://doi.org/10.3109/02844318309013125
  4. Roses DF, Valensi Q La Trenta G, Harris MN: Surgical treatment of dermatofibrosarcoma protuberans. Surg Gynecol Obstet 162: 449, 1986
  5. Mark RJ, Bailet JW, Tran LM, Poen J, Fu YS, Calcaterra TC: Dermatofibrosarcoma protuberans of the head and neck: A report of 16 cases. Arch Otolaryngol Head Neck Surg 119: 891, 1993 https://doi.org/10.1001/archotol.1993.01880200097014
  6. McPeak CJ, Cruz T, Nicastri AD: Dermatofibrosarcoma protuberans: An analysis of 86 cases-5 with metastasis. Ann Surg 166: 803, 1967 https://doi.org/10.1097/00000658-196711000-00011
  7. Rutgers EJ, Kroon BB, Albus-Lutter CE, Gortzak E: Dermatofibrosarcoma protuberans: treatment and prognosis. Eur J Surg Oncol 18: 241, 1992
  8. Fletcher CD, Evans BJ, MacArtney JC, Smith N, Jones EW, Mckee PH: Dermatofibrosarcoma protuberans: A clinicopathological and immunohistochemical study with a review of the literature. Histopathology 9: 921, 1985 https://doi.org/10.1111/j.1365-2559.1985.tb02878.x
  9. Gloster HM, Harris KR, Roenigk RK: A Comparison between Mohs micrographic surgery and wide surgical excision for the treatment of dermatofibrosarcoma protuberans. J Am Acad Dermatol 35: 82, 1996 https://doi.org/10.1016/S0190-9622(96)90159-0
  10. Ratner D, Thomas CO, Johnson TM, Sondak VK, Hamilton TA, Nelson BR, Swanson NA, Garcia C, Clark RE, Grande DJ: Mohs micrographic surgery for the treatment of dermatofibrosarcoma protuberans. J Am Aead Dermatol 37: 600, 1997 https://doi.org/10.1016/S0190-9622(97)70179-8
  11. Wacker J, Khan-Durani B, Hartschuh W: Modified Mohs Micrographic Surgery in the Therapy of Dermatofibrosarcoma Protuberans: Analysis of 22 Patients. Ann Surg Oncol 11: 438, 2004 https://doi.org/10.1245/ASO.2004.06.014
  12. Mark LB, Suit HD, Phil D, Rosenberg AE, Wood WC: Dermatofibrosarcoma protuberans treated with radiation therapy. Int J Radiat Oncol Biol Phys 17: 379, 1989 https://doi.org/10.1016/0360-3016(89)90454-9