우리나라 양돈장에서 Mycoplasma hyopneumoniae 유병율 조사

Seroprevalence of Mycoplasma hyopneumoniae infection in Korean swine herds

  • 심사 : 2005.02.28
  • 발행 : 2005.03.25

초록

Serum samples of 1,175 pigs from 148 Korean swine farms not using Mycoplasma hyopneumoniae (M. hyo) vaccines were collected for seroepidemiological study of M. hyo infection by indirect ELISA method. Informations of each farm were provided about province where the farm was located and season when blood samples were collected. Then, the selected farms were divided into farm units which had 5 serum samples according to production stages : sow, suckling piglet (<30 days old), nursery pig (30-70 days old), and growing pig (>70 days old). Seroprevalence of M. hyo infection according to production stages, province, and season was investigated by using ELISA-positve rate of the selected samples for each study. This study showed that 85.34% (78.94-91.78%, 95% CI) of farms were positive to M. hyo infection and 34.81% (32.09-37.53%, 95% CI) among pigs were sero-positive to M. hyo infection in Korean swine farms. In the study of seroprevalence by production stage, most farms had sows and growing pigs which were sero-positive to M. hyo infection (sow: 83.05%, growing pigs: 87.72%) and most pigs seemed to be naturally infected by M. hyo at 8-10 weeks of age. Also, M. hyo infection showed seasonal pattern that most pigs were infected in late fall to early winter. However, in the study of seroprevalence by province, there was no significant correlation between province and M. hyo sero-positive rate.

키워드

참고문헌

  1. Blanchard B, Vena MM, Cavalier A, Le Lannic J, Gouranton J, Kobisch M. Electron microscopic observation of the respiratory tract of SPF piglets inoculated with Mycoplasma hyopneumoniae. Vet Microbiol 1992, 30, 329-341 https://doi.org/10.1016/0378-1135(92)90020-T
  2. Cho KH, Choi JS, Kim BH. Survey on mycoplasmal pneumonia of swine in Yongnam area and antimicrobial susceptibility of Mycoplasma hyopneumoniae isolated from slaughter pigs. Korean J Vet Res 1998, 39, 96-103
  3. Clark LK, Scheidt AB, Armstrong CH, Knox K, Mayrose VB. The effects of all-in/all-out management on pigs from a herd with enzootic pneumonia. Vet Med 1991, 9, 946-951
  4. Dungworth DL. The respiratory system. In: Jubb KFC, Kennedy PC, Palmer N(ed.). Pathology of Domestic Animals, 4th ed., pp. 661-663, Academic Press, New York, 1993
  5. Gardner IA, Hird DW. Host determinants of pneumonia in slaughter weight swine. Am J Vet Res 1990, 51, 1306-1311
  6. Goodwin RFW, Pomeroy AP, Whittlestone P. Production of enzootic pneumonia in pigs with a mycoplasma. Vet Rec 1965, 77, 1247-1249
  7. Kazama S, Yagihashi T, Seto K. Preparation of Mycoplasma hyopneumoniae antigen for the enzymelinked immunosorbent assay. Can J Vet Res 1989, 53, 176-181
  8. Kim HK, Kim EM, Moon HJ, Kim TY, Lim JS, Lee YH, Park BK. Analysis of Mycoplasma hyopneumoniae infection by seroepidemiological investigation in Korean swine herds. Korean J Vet Res 2004, 44, 587-591
  9. Kobisch M, Blanchard B, Le Potier MF. Mycoplasma hyopneumoniae infection in pigs: duration of the disease and resistance to infection. Vet Res 1993, 24, 67-77
  10. Morris CR, Gardner IA, Hietala SK, Carpenter TE, Anderson RJ, Parker KM. Seroepidemiologic study of natural transmission of Mycoplasma hyopneumoniae in a swine herd. Prev Vet Med 1995, 21, 323-337 https://doi.org/10.1016/0167-5877(94)00384-U
  11. Nicolet J, Zimmerman W, Chastonay M. Epidemiology and serodiagnosis of Mycoplasma hyopneumoniae. Zentralblatt Bakterol 1990, 20(suppl.), 249-253
  12. Sheldrake RF, Gardner IA, Saunders MM, Romalis LF. Serum antibody response to Mycoplasma hyopneumoniae measured by enzyme-linked immunosorbent assay after experimental and natural infection of pigs. Aust Vet J 1990, 67, 39-42 https://doi.org/10.1111/j.1751-0813.1990.tb07691.x
  13. Stark KD, Nicolet J, Frey J. Detection of Mycoplasma hyopneumoniae by air sampling with a nested PCR assay. Appl Environ Microbiol 1998, 64, 543-548
  14. Vicca J, Maes D, Thermote L, Peeters J, Haesebrouck F, de Kruif A. Patterns of Mycoplasma hyopneumoniae infections in Belgian farrow-to-finish pig herds with diverging disease-course. J Vet Med B 2002, 49, 349-353 https://doi.org/10.1046/j.1439-0450.2002.00579.x
  15. Wallgren P, Bolske G, Gustafsson S, Mattsson S, Fossum C. Humoral immune responses to Mycoplasma hyopneumoniae in sows and offspring following an outbreak of mycoplasmosis. Vet Microbiol 1998, 60, 193-205 https://doi.org/10.1016/S0378-1135(98)00155-2
  16. Yagihashi T, Kazama S, Tajima M. Seroepidemiology of Mycoplasmal pneumoniae of swine in Japan as surveyed by an enzyme-linked immunosorbent assay. Vet Microbiol 1993, 34, 155-166 https://doi.org/10.1016/0378-1135(93)90169-8