Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
권호 표지

항-U1RNP 항체 양성인 신생아 홍반성 루푸스 1례

A Case of Neonatal Lupus Erythematosus Associated with Anti-U1RNP Antibodies

  • 안병훈 (충북대학교 의과대학 소아과학교실) ;
  • 이구창 (충북대학교 의과대학 피부과학교실 & 의학연구소) ;
  • 윤태영 (충북대학교 의과대학 피부과학교실 & 의학연구소) ;
  • 김미정 (충북대학교 의과대학 소아과학교실)
  • An, Byung-Hoon (Department of Pediatrics, College of Medicine, Chungbuk National University) ;
  • Lee, Gu Chang (Department of Dermatology & Medical Research Institute, College of Medicine, Chungbuk National University) ;
  • Yoon, Tae Young (Department of Dermatology & Medical Research Institute, College of Medicine, Chungbuk National University) ;
  • Kim, Mi-Jung (Department of Pediatrics, College of Medicine, Chungbuk National University)
  • 투고 : 2004.09.07
  • 심사 : 2004.10.13
  • 발행 : 2005.03.15
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초록

저자들은 전신성 홍반성 루푸스 산모에서 출생한 생후 1개월된 신생아에서 매우 드물게 나타나는 항-$U_1RNP$ 항체 양성으로 인한 신생아 홍반성 루푸스 1례를 경험하였기에 그 임상적 특징을 문헌고찰과 함께 보고하는 바이다.

Neonatal lupus erythematosus(NLE) is a distinct subset of lupus characterized by cutaneous findings, cardiac conduction defects, hepatic or hematologic abnormalities. These manifestations are associated with the presence of maternal auto-antibodies such as anti-SSA/Ro, anti-SSB/La, and rarely anti-RNP($U_1RNP$) antibodies. Cases of $U_1RNP$ antibody-positive NLE have somewhat atypical cutaneous manifestation without cardiac or systemic abnormalities. We report a case of cutaneous NLE associated with $U_1RNP$ antibodies.

키워드

참고문헌

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