참고문헌
- Aichele, P., Brduscha-Reim, K., Oehen, S., Odermatt, B., Zinkernagel, R. M., Hengartner, H. and Pircher, H. (1995) Brief definitive report: T cell priming versus T cell tolerance induced by synthetic peptides. J. Exp. Med. 182, 261-266 https://doi.org/10.1084/jem.182.1.261
- Aichele, P., Brduscha-Reim, K., Oehen, S., Odermatt, B., Zinkernagel, R. M., Hengartner, H. and Pircher, H. (1997) Peptide antigen treatment of naïve and virus-immune mice: antigen-specific tolerance versus immunopathology. Immunity 6, 519-529 https://doi.org/10.1016/S1074-7613(00)80340-4
- Blichfeldt, E., Munthe, L. A., Rotnes, J. S. and Bogen, B. (1996) Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor. Eur. J. Immunol. 26, 2876-2884 https://doi.org/10.1002/eji.1830261211
- von Boehmer, H. (1993) Developmental biology of T cells in T cell receptor transgenic mice. Ann. Rev. Immunol. 8, 531-556 https://doi.org/10.1146/annurev.immunol.8.1.531
- von Boehmer, H. and Kisielow, P. (1998) Self-nonself discrimination by T cells. Science 248, 1369-1373 https://doi.org/10.1126/science.1972594
- Borgulya, P., Kishi, H., Uematsu, Y. and von Boehmer, H. (1992) Exclusion and inclusion of and T cell receptor alleles. Cell 69, 529-537 https://doi.org/10.1016/0092-8674(92)90453-J
- Burkly, L. C., Lo, D., Kangawa, O., Brinster, R. L. and Flavall, R. A. (1989) T-cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC II I-E. Nature 342, 564- 566 https://doi.org/10.1038/342564a0
- Casanova, I. L., Romero, P., Widmann, C., Kourilsky, P. and Maryanski, J. L. (1991) T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implication for T cell allelic exclusion and antigen-specific repertoire. J. Exp. Med. 174, 1371-1383 https://doi.org/10.1084/jem.174.6.1371
- Daniels, M. A., Schober, S. L., Hogquist, K. A. and Jameson, S. C. (1999) Cutting edge: a test of the dominant negative signal model for TCR antagonism. J. Immunol. 163, 1750-1754
- Dittel, B. N., Stefanova, I. and Germaim, R. N. (1999) Crossantagonism of a T cell clone expressing two distinct T cell receptors. Immunity 11, 289-298 https://doi.org/10.1016/S1074-7613(00)80104-1
- Ferber, I., Schonrich, G., Schenkel, J., Mellor, A. L., Hammerling, G. J. and Arnold, B. (1994) Levels of peripheral T-cell tolerance induced by different doses of tolerogen. Science 263, 674-676 https://doi.org/10.1126/science.8303275
- Fossati, G., Cooke, A., Papafio, R. Q., Haskins, K. and Stokinger, B. (1999) Triggering a second T cell receptor on diabetogenic T cells can prevent induction of diabetes. J. Exp. Med. 190, 577-583 https://doi.org/10.1084/jem.190.4.577
- George, Y. L., Fairchild, P. J., Smith, R. M., Prowle, J. R., Kioussis, D. and Wraith, D. C. (1995) Low avidity recognition of self-antigen by T cells permits escape from central tolerance. Immunity 3, 407-415 https://doi.org/10.1016/1074-7613(95)90170-1
- Hammering, G. J., Schonrich, G., Ferber, I. and Arnold, B. (1993) Peripheral tolerance as a multistep mechanism. Immunol. Rev. 133, 93-104 https://doi.org/10.1111/j.1600-065X.1993.tb01511.x
- Heath, W. R. and Miller, J. F. A. P. (1993) Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice. J. Exp. Med. 178, 1807-1811 https://doi.org/10.1084/jem.178.5.1807
- Heath, W. R., Carbone, F. R., Bertolino, P., Kelly, J., Cose, S. and Miller, J. F. A. P. (1995) Expression of two T cell receptor a chains on the surface of normal murine T cells. Eur. J. Immunol. 25, 1617-1623 https://doi.org/10.1002/eji.1830250622
- Janeway, C. A. (1992) The T cell receptor as a multicomponent signaling machine: CD4/CD8 coreceptors and CD45 in T cell activation. Annu. Rev. Immunol. 10, 645-674 https://doi.org/10.1146/annurev.iy.10.040192.003241
- Kappler, J. W., Roehm, N. and Marrack, P. (1987) T cell tolerance by clonal elimination in the thymus. Cell 49, 273-280 https://doi.org/10.1016/0092-8674(87)90568-X
- Kappler, J. W., Staerz, U. D., White, J. and Marrack, P. (1988) Self tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex. Nature 332, 35-40 https://doi.org/10.1038/332035a0
- Kaye, J., Hsu, M., Sauron, M., Jameson, S. C., Gascoigne, N. R. J. and Hedrick, S. M. (1989) Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature 341, 746-749 https://doi.org/10.1038/341746a0
- Kyburz, D., Aichele, P., Speiser, D. E., Hengartner, H., Zinkernagel, R. M. and Pircher, H. (1993) T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptide. Eur. J. Immunol. 23, 1956-1962 https://doi.org/10.1002/eji.1830230834
-
MacDonald, H. R., Schineider, R., Lees, R. K., Howe, R. C., Acha-Orbea, H., Festenstein, H., Zinkernagel, R. M. and Hengartner, H. (1988) T cell receptor V
$\beta$ use predicts reactivity and tolerance to Misa-encoded antigens. Nature 332, 40-45 https://doi.org/10.1038/332040a0 - Miller, J. F. A. P. and Morahan, G. (1992) Peripheral T Cell Tolerance. Annu. Rev. Immunol. 10, 51-69 https://doi.org/10.1146/annurev.iy.10.040192.000411
- Moscophidis, D., Lechner, F., Pircher, H. P. and Zinkernagel, R. M. (1993) Virus persistence in acutely infected immunocompetent mice by exhausting of antiviral cytotoxic effector T cells. Nature 362, 758-761 https://doi.org/10.1038/362758a0
- Ohashi, P. S., Oehen, S., Buerki, K., Pirdher, H., Ohashi, C. T., Odermatt, B., Malissen, B., Zinkernagel, R. M. and Hengartner, H. (1991) Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 65, 305- 317 https://doi.org/10.1016/0092-8674(91)90164-T
- Oldstone, M. B. (1987) Molecular mimicry and autoimmune disease. Cell 50, 819-820 https://doi.org/10.1016/0092-8674(87)90507-1
- Padovan, E., Casorati, G., Dellabona, P., Meyer, S., Brockhaus, M. and Lanzavecchia, A. (1993) Expression of two T cell receptor a chains: dual receptor T cells. Science 262, 422-424 https://doi.org/10.1126/science.8211163
- Pircher, H., Burki, K., Lang, R., Hengartner, H. and Zinkernagel, R. M. (1989) Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342, 559- 561 https://doi.org/10.1038/342559a0
- Racioppi, L., Matarese, G., Doro, U., Pascale, M., Masci, A. M., Fontana, S. and Zappacosta, S. (1996) The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling. Proc. Natl. Acad. Sci. USA 93, 10360-10365
-
Rammensee, H. G., Krosschewski, R. and Frangoulis, B. (1989) Clonal anergy induced in mature
$V\beta6^{+}$ T lymphocytes on immunizing Mis-1 mice with Mis-1 expression cells. Nature 339, 541-544 https://doi.org/10.1038/339541a0 -
Robertson, J. M. and Evavold, B. D. (1999) Cutting edge: dueling TCRs: peptide antagonism of
$CD4^{+}$ T cells with dual antigen specificities. J. Immunol. 63, 1750-1754 - Rocha, B. and von Boehmer, H. (1991) Peripheral selection of the T cell repertoire. Science 251, 1225-1228 https://doi.org/10.1126/science.1900951
- Rocken, M., Urban, J. F. and Shevach, E. M. (1992) Infection breaks T-cell tolerance. Nature 359, 79-82 https://doi.org/10.1038/359079a0
-
Sarukhan, A., Garcia, C., Lanoue, A. and von Boehmer, H. (1998) Allelic inclusion of T cell receptor
$\alpha$ genes poses an autoimmune hazard due to low-level expression of autospecific receptors. Immunity 8, 563-570 https://doi.org/10.1016/S1074-7613(00)80561-0 - Schild, H. J., Rotzschje, O., Kalbacher, H. and Rammensee, H. G. (1990) Limit of T cell tolerance to self-proteins by peptide presentation. Science 247, 1587-1589 https://doi.org/10.1126/science.2321019
- Sha, W. C., Nelson, C. A., Newberry, R. D., Kranz, D. M., Russell, J. H. and Loh, D. Y. (1988) Positive and negative selection of an antigen receptor on T cells transgenic mice. Nature 1336, 73-76 https://doi.org/10.1038/336073a0
- Stotz, S. H., Bolliger, L., Carbone, F. R. and Palmer, E. (1999) T cell receptor (TCR) antagonism without a negative signal: evidence from T cell hybridomas expressing two independent TCRs. J. Exp. Med. 189, 253-263 https://doi.org/10.1084/jem.189.2.253
- Webb, S., Morris, C. and Sprent, J. (1990) Extrathymic tolerance of mature cells: clonal elimination as a consequence of immunity. Cell 63, 1249-56 https://doi.org/10.1016/0092-8674(90)90420-J
- Zal, T., Weiss, S., Mellor, A. and Stockinger, B. (1996) Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function. Proc. Natl. Acad. Sci. USA 93, 9102-9107
- Zal, T., Zal, M. A. and Gascoigne, N. R. J. (2002) Inhibition of T cell receptor-coreceptor interactions by antagonist ligands visualized by live FRET imaging of the T-hybridoma immunological synapse. Immunity 16, 521-534 https://doi.org/10.1016/S1074-7613(02)00301-1
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