과제정보
연구 과제번호 : Chemical Genomics Research Project
연구 과제 주관 기관 : MOST (Ministry of Science and Technology), Korea Research Institute of Chemical Technology
참고문헌
- Balabanov, S., Zimmermann, U., Protzel, C., Scharf, C., Klebingat, K. J., et al. (2001) Tumor-related enzyme alterations in the clear cell type of human renal cell carcinoma identified by two-dimensional gel electrophoresis. Eur. J. Biochem. 268, 5977-5980 https://doi.org/10.1046/j.0014-2956.2001.02546.x
- Beliakoff, J. and Whitesell, L. (2004) Hsp90: an emerging target for breast cancer therapy. Anticancer Drugs 15, 651-662 https://doi.org/10.1097/01.cad.0000136876.11928.be
- Cappello, F., Bellafiore, M., Palma, A., David, S., Marciano, V., et al. (2003) 60 Kda chaperonin (HSP60) is over-expressed during colorectal carcinogenesis. Eur. J. Histochem. 47, 105-110
- Cappello, F., Bellafiore, M., Palma, M. A., Marciano, V., Martorana, G., et al. (2002-2003) Expression of 60-kDa heat shock protein increases during carcinogenesis in the uterine exocervix. Pathobiology 70, 83-88 https://doi.org/10.1159/000067304
- Clemons, M. and Goss, P. (2001) Estrogen and the risk of breast cancer. N. Engl. J. Med. 344, 276-285 https://doi.org/10.1056/NEJM200101253440407
- Cook, R. M., Franklin, W. A., Moore, M. D., Johnson, B. E., and Miller, Y. E. (1998) Mutational inactivation of aminoacylase- I in a small cell lung cancer cell line. Genes Chromosomes Cancer 21, 320-325 https://doi.org/10.1002/(SICI)1098-2264(199804)21:4<320::AID-GCC5>3.0.CO;2-0
- Csermely, P., Schnaider, T., Soti, C., Prohaszka, Z., and Nardai, G. (1998) The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review. Pharmacol. Ther. 79, 129-168 https://doi.org/10.1016/S0163-7258(98)00013-8
- Curmi, P. A., Nogues, C., Lachkar, S., Carelle, N., Gonthier, M. P., et al. (2000) Overexpression of stathmin in breast carcinomas points out to highly proliferative tumours. Br. J. Cancer 82, 142-150 https://doi.org/10.1054/bjoc.1999.0891
- Darbre, P., Yates, J., Curtis, S., and King, R. J. (1983) Effect of estradiol on human breast cancer cells in culture. Cancer Res. 43, 349-354
- Ernst, M., Schmid, C., and Froesch, E. R. (1989) Phenol red mimics biological actions of estradiol: enhancement of osteoblast proliferation in vitro and of type I collagen gene expression in bone and uterus of rats in vivo. Steroid Biochem. 33, 907-914 https://doi.org/10.1016/0022-4731(89)90239-2
- Fishman, J. and Martucci, C. (1980) Biological properties of 16 alpha-hydroxyestrone: implications in estrogen physiology and pathophysiology. Clin. Endocrinol Metab. 51, 611-615 https://doi.org/10.1210/jcem-51-3-611
- Fishman, J., Schneider, J., Hershcope, R. J., and Bradlow, H. L. (1984) Increased estrogen-16 alpha-hydroxylase activity in women with breast and endometrial cancer. Steroid Biochem. 20, 1077-1081 https://doi.org/10.1016/0022-4731(84)90021-9
-
Flouriot, G., Brand, H., Denger, S., Metivier, R., Kos, M., et al. (2000) Identification of a new isoform of the human estrogen receptor-
${\alpha}$ (hER-${\alpha}$ ) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1. EMBO J. 19, 4688-4700 https://doi.org/10.1093/emboj/19.17.4688 - Frydman, J. and Hart, F. U. (1996) Principles of chaperoneassisted protein folding: differences between in vitro and in vivo mechanisms. Science 272, 1497-1502 https://doi.org/10.1126/science.272.5267.1497
- Gupta, M., McDougal, A., and Safe, S. (1998) Estrogenic and antiestrogenic activities of 16alpha- and 2-hydroxy metabolites of 17beta-estradiol in MCF-7 and T47D human breast cancer cells. J. Steroid Biochem. Mol. Biol. 67, 413-419 https://doi.org/10.1016/S0960-0760(98)00135-6
- Horwitz, K. B. and McGuire, W. L. (1978) Estrogen control of progesterone receptor in human breast cancer. Correlation with nuclear processing of estrogen receptor. J. Biol. Chem. 253, 2223-2228
- Hwang, T. S., Han, H. S., Choi, H. K., Lee, Y. J., Kim, Y. J., et al. (2003) Differential, stage-dependent expression of Hsp70, Hsp110 and Bcl-2 in colorectal cancer. J. Gastroenterol. Hepatol. 18, 690-700 https://doi.org/10.1046/j.1440-1746.2003.03011.x
- Isaacs, J. S., Xu, W., and Neckers, L. (2003) Heat shock protein 90 as a molecular target for cancer therapeutics. Cancer Cell 3, 213-217 https://doi.org/10.1016/S1535-6108(03)00029-1
-
Kim, S. H., Lee, S., Kim, M. H., Kim, B. T., and Min, Y. K. (2005) Protein profiling and transcript expression levels of heat shock proteins in 17
${\beta}$ -estradiol-treated human MCF-7 breast cancer cells. (submitted) - Kumar, P., Mark, P. J., Ward, B. K., Minchin, R. F., and Ratajczak, T. (2001) Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells. Biochem. Biophys. Res. Commun. 284, 219-225 https://doi.org/10.1006/bbrc.2001.4952
- Lewis, J. S., Thomas, T. J., Klinge, C. M., Gallo, M. A., and Thomas, T. (2001) Regulation of cell cycle and cyclins by 16alpha-hydroxyestrone in MCF-7 breast cancer cells. J. Mol. Endocrinol. 27, 293-307 https://doi.org/10.1677/jme.0.0270293
- Li, J. J. and Li, S. A. (1987) Estrogen carcinogenesis in Syrian hamster tissues: role of metabolism. Fed. Proc. 46, 1858-1863
- Liehr, J. G. and Ricci, M. J. (1996) 4-Hydroxylation of estrogens as marker of human mammary tumors. Proc. Natl. Acad. Sci. USA 93, 3294-3296
- Liehr, J. G., Fang, W. F., Sirbasku, D. A., and Ari-Ulubelen, A. (1986) Carcinogenicity of catechol estrogens in Syrian hamsters. J. Steroid Biochem. 24, 353-356 https://doi.org/10.1016/0022-4731(86)90080-4
- Lippert, T. H., Seeger, H., and Mueck, A. O. (2000) The impact of endogenous estradiol metabolites on carcinogenesis. Steroids 65, 357-369 https://doi.org/10.1016/S0039-128X(00)00101-X
- Lippert, C., Seeger, H., and Mueck, A. O. (2003) The effect of endogenous estradiol metabolites on the proliferation of human breast cancer cells. Life Sci. 72, 877-883 https://doi.org/10.1016/S0024-3205(02)02305-6
- Liu, Z. J. and Zhu, B. T. (2004) Concentration-dependent mitogenic and antiproliferative actions of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells. J. Steroid Biochem. Mol. Biol. 88, 265-275 https://doi.org/10.1016/j.jsbmb.2003.12.003
-
Livak, K. J. and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the
$2^{-{\Delta}{\Delta}{\Delta}C}T$ method. Methods 25, 402-408 https://doi.org/10.1006/meth.2001.1262 - Lorenzo, J. (2003) A new hypothesis for how sex steroid hormones regulate bone mass. J. Clin. Invest. 111, 1641-1643 https://doi.org/10.1172/JCI18812
- McGuire, W. L., Horwitz, K. B., Chamness, G. C., and Zava, D. T. (1976) A physiological role for estrogen and progesterone in breast cancer. J. Steroid Biochem. 7, 875-882 https://doi.org/10.1016/0022-4731(76)90005-4
- Nardulli, A. M., Greene, G. L., O'Malley, B. W., and Katzenellenbogen, B. S. (1988) Regulation of progesterone receptor messenger ribonucleic acid and protein levels in MCF-7 cells by estradiol: analysis of estrogen's effect on progesterone receptor synthesis and degradation. Endocrinology 122, 935-944 https://doi.org/10.1210/endo-122-3-935
- Newbold, R. R. and Liehr, J. G. (2000) Induction of uterine adenocarcinoma in CD-1 mice by catechol estrogens. Cancer Res. 60, 235-237
- Oh, W. K. and Song, J. (2003) Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation. Mol. Cells 16, 84-91
- Peattie, D. A., Harding, M. W., Fleming, M. A., DeCenzo, M. T., Lippke, J. A., et al. (1992) Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes. Proc. Natl. Acad. Sci. USA 89, 10974-10978
- Rogan, E. G., Badawi, A. F., Devanesan, P. D., Meza, J. L., Edney, J. A., et al. (2003) Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer. Carcinogenesis 24, 697-702 https://doi.org/10.1093/carcin/bgg004
- Rozen, S. and Skaletsky, H. J. (2000) Primer3 on the WWW for general users and for biologist programmers; in Bioinformatics Methods and Protocols: Methods in Molecular Biology, Krawetz, S. and Misener, S. (eds.), pp. 365-386, Humana Press, Totowa
- Schneider, J., Kinne, D., Fracchia, A., Pierce, V., Anderson, K. E., et al. (1982) Abnormal oxidative metabolism of estradiol in women with breast cancer. Proc. Natl. Acad. Sci. USA 79, 3047-3051
- Schumacher, G. and Neuhaus, P. (2001) The physiological estrogen metabolite 2-methoxyestradiol reduces tumor growth and induces apoptosis in human solid tumors. J. Cancer Res. Clin. Oncol. 127, 405-410 https://doi.org/10.1007/s004320000233
- Schutze, N., Vollmer, G., Tiemann, I., Geiger, M., and Knuppen, R. (1993) Catecholestrogens are MCF-7 cell estrogen receptor agonists. J. Steroid Biochem. Mol. Biol. 46, 781-789 https://doi.org/10.1016/0960-0760(93)90319-R
- Seegers, J. C., Aveling, M. L., Van Aswegen, C. H., Cross, M., Koch, F., et al. (1989) The cytotoxic effects of estradiol-17 beta, catecholestradiols and methoxyestradiols on dividing MCF-7 and HeLa cells. J. Steroid Biochem. 32, 797-809 https://doi.org/10.1016/0022-4731(89)90455-X
-
Soufla, G., Porichis, F., Sourvinos, G., Vassilaros, S., and Spandidos, D. A. (2005) Transcription deregulation of VEGF, FGF2, TGF-
${\betha}$ 1, 2, 3 and cognate receptors in breast tumorigenesis. Cancer Lett. [Epud ahead of print] - Swaneck, G. E. and Fishman, J. (1988) Covalent binding of the endogenous estrogen 16 alpha-hydroxyestrone to estradiol receptor in human breast cancer cells: characterization and intranuclear localization. Proc. Natl. Acad. Sci. USA 85, 7831-7835
- Wang, X. Y., Chen, X., Manjili, M. H., Repasky, E., Henderson, R., et al. (2003) Targeted immunotherapy using reconstituted chaperone complexes of heat shock protein 110 and melanoma- associated antigen gp100. Cancer Res. 63, 2553-2560
- Ward, B. K., Mark, P. J., Ingram, D. M., Minchin, R. F., and Ratajczak, T. (1999) Expression of the estrogen receptorassociated immunophilins, cyclophilin 40 and FKBP52, in breast cancer. Breast Cancer Res. Treat. 58, 267-280