Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics (대한후두음성언어의학회지)

The Korean Society of Laryngology, Phoniatrics and Logopedics. (대한후두음성언어의학회)
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Three Cases of Neuroendocrine Carcinoma of the Larynx

후두에 발생한 신경 내분비암종 3예

  • Yeo, Nam-Kyung (Department of Otorhinolaryngology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Choi, Seung-Ho (Department of Otorhinolaryngology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Sang-Yoon (Department of Otorhinolaryngology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Nam, Soon-Yuhl (Department of Otorhinolaryngology, Asan Medical Center, University of Ulsan College of Medicine)
  • 여남경 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 최승호 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 김상윤 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 남순열 (울산대학교 의과대학 서울아산병원 이비인후과학교실)
  • Published : 2005.06.01
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Abstract

Although primary neuroendocrine carcinomas(NEC) are uncommon tumors of the larynx, they represent the most common nonepidermoid malignancy of this organ. Whereas typical carcinoid tumors and small-cell carcinomas occur very rarely in the larynx, the majority of laryngeal NEC belong to a broad intermediate group between these two extremes of NEC. Through many case studies, a major protion of clinicopathologic characteristics of laryngeal NEC have been revealed; however, the gistogenesis of laryngeal NEC is still unknown. The only well-documented normal neuroendocrine structures of the larynx are paraganglions, but the incidence of laryngeal paragangliomas are much lower than that of NEC. Here, we report on three cases of NEC affecting the larynx and the results of searching for neuroendocriene cells in non-neoplastic larynx tissue.

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