Archives of Pharmacal Research

  • 제28권11호
  • /
  • Pages.1219-1223
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  • 2005
  • /
  • 0253-6269(pISSN)
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  • 1976-3786(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Synthesis of 6-[2-(Benzoxazol-2-ylmethylamino )ethoxy]-1-Alkyl­1 H-lndole-2-Carboxylic Acid and Inhibitory Activity on $\beta$-Amyloid Aggregation

  • Lee, Sun-Mi (College of Pharmacy, Sookmyung Women's University) ;
  • Jeon, Raok (College of Pharmacy, Sookmyung Women's University)
  • 발행 : 2005.11.01
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초록

6-[2-(Benzoxazol-2-ylmethylamino)ethoxy]-1-alkyl-1H-indole-2-carboxylic acids were designed and synthesized as $\beta$-amyloid (A$\beta$) fibril assembly inhibitors. Their inhibitory activity on A$\beta$, aggregation was evaluated by thioflavin T assay although their activities were insignificant.

키워드

참고문헌

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