Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics (대한후두음성언어의학회지)

The Korean Society of Laryngology, Phoniatrics and Logopedics. (대한후두음성언어의학회)
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The Effect of Artecoll Injection for the Patients with Unilateral Vocal Cord Paralysis

일측성 성대마비 환자에서 Artecoll을 이용한 성대주입술의 효과 및 안전성

  • Oh Jae-Won (Department of Otorhinolaryngology-Head and Neck Surgery, Sungkyunkwan University School of Medicine) ;
  • Lee Seung-Won (Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Soonchunhyang University) ;
  • Kim Min-Beom (Department of Otorhinolaryngology-Head and Neck Surgery, Sungkyunkwan University School of Medicine) ;
  • Yun Young-Sun (Department of Otorhinolaryngology-Head and Neck Surgery, Sungkyunkwan University School of Medicine) ;
  • Kim Kwan-Min (Department of Thoracic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Son Young-Ik (Department of Otorhinolaryngology-Head and Neck Surgery, Sungkyunkwan University School of Medicine)
  • 오재원 (성균관대학교 의과대학 삼성서울병원 이비인후과학교실) ;
  • 이승원 (순천향대학교 의과대학 이비인후과학교실) ;
  • 김민범 (성균관대학교 의과대학 삼성서울병원 이비인후과학교실) ;
  • 윤영선 (성균관대학교 의과대학 삼성서울병원 이비인후과학교실) ;
  • 김관민 (성균관대학교 의과대학 삼성서울병원 흉부외과학교실) ;
  • 손영익 (성균관대학교 의과대학 삼성서울병원 이비인후과학교실)
  • Published : 2005.11.01
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Abstract

Background and Objectives : Artecoll(R) is an injectable soft tissue filler, which is a suspension of polymethylmethacrylate microspheres in $3.5\%$ bovine collagen solution. The authors aimed to determine the clinical of Artecoll of Artecoll(R) as an injection material into the vocal fold to correct the glottal insufficiency caused by unilateral vocal cord paralysis. Materials and Methods : Forty-one consecutive patients with unilateral vocal cord paralysis received percutaneous Artecoll injections under local anesthesia. Acoustic, aerodynamic and stroboscopic analyses were prospectively provided before, 1 week and 3 months after injection. Perceptual GRBAS grading by speech language pathologists and subjective ratings of the hoarseness and aspiration by the patients were also obtained. Results : Aerodynamic parameter(maximal phonation time) were significantly improved after the injection (p<0.05). Acoustic parameters (jitter and shimmer) were improved at the 3rd month follow-up. GRBAS uading and patients own subjective scaling of hoarseness and aspiration also showed significant improvement (p<0.05). Early or delayed significant side effects were not observed. Conclusion : Vocal fold injection with Artecoll is a convenient, safe and useful method of temporarily correcting the glottal insufficiency. Further long-term follow-up studies will answer the usefulness and safety of the Artecoll injection laryngoplasty.

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