Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
권호 표지

Effects of Boron Supplementation on Lipid Profiles and Antioxidant Capacities in the Ovariectomized Rats

난소절제 흰쥐에 있어 붕소 보충이 지질패턴과 항산화능에 미치는 영향

  • Choi Mi-Kyeone (Department of Human Nutrition h Food Scienece Chungwoon University) ;
  • Kang Myung-Hwn (Department of Food Science & Nutrition Hoseo University)
  • 최미경 (청운대학교 식품영양학과) ;
  • 강명화 (호서대학교 식품영양학과)
  • Published : 2005.11.01
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Abstract

The purpose of this research was to investigate the effect of the boron supplementation on lipid profiles and antioxidant capacities in ovariectomized (OVX) rats. Rats were divided into 3 groups and fed diet with intake levels of boron (0.5 ppm,50 ppm,100 ppm) for 4 weeks. The half of rats in each group was ovariectomized and the others were sham-operated. And rats were fed same diets for 8 weeks after operation. Feed intake and weight gain were significantly increased by increasing boron intake and higher in OVX group than those in sham-operated. FER was significantly higher in OVX group than that of sham-operated. There were no significant differences in serum lipid profiles among the groups. The contents of hepatic total lipid were significantly higher in OVX group than those of sham-operated and the lowest in high-boron group. Hepatic GST activity was significantly decreased by ovariectomy and the lowest in very high-boron group. Hepatic catalase activity was the lowest in high-boron group of OVX. Hepatic TBARS level of high-boron group was the lowest in sham-operated groups. Hepatic TBARS level induced by AAPH was significantly decreased by increasement of boron supplementation. Taken together, this results suggest that the boron supplementation have the potential role for improving lipid profiles and antioxidant capacities in OVX rats.

Keywords

References

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