Genomics & Informatics

Korea Genome Organization (한국유전체학회)
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Development of a Knowledge Base for Korean Pharmacogenomics Research Network

  • Park, Chan Hee (Seoul National University Biomedical Informatics (SNUBI), Seoul National University College of Medicine) ;
  • Lee, Su Yeon (Seoul National University Biomedical Informatics (SNUBI), Seoul National University College of Medicine) ;
  • Jung, Yong (Seoul National University Biomedical Informatics (SNUBI), Seoul National University College of Medicine) ;
  • Park, Yu Rang (Seoul National University Biomedical Informatics (SNUBI), Seoul National University College of Medicine) ;
  • Lee, Hye Won (Seoul National University Biomedical Informatics (SNUBI), Seoul National University College of Medicine) ;
  • Kim, Ju Han (Seoul National University Biomedical Informatics (SNUBI), Seoul National University College of Medicine)
  • Published : 2005.09.01
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Abstract

Pharmacogenomics research requires an intelligent integration of large-scale genomic and clinical data with public and private knowledge resources. We developed a web-based knowledge base for KPRN (Korea Pharmacogenomics Research Network, http://kprn.snubi. org/). Four major types of information is integrated; genetic variation, drug information, disease information, and literature annotation. Eighteen Korean pharmacogenomics research groups in collaboration have submitted 859 genotype data sets for 91 disease-related genes. Integrative analysis and visualization of the large collection of data supported by integrated biomedical path­ways and ontology resources are provided with a user-friendly interface and visualization engine empowered by Generic Genome Browser.

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