대한물리치료과학회지 (Journal of Korean Physical Therapy Science)
- 제12권4호
- /
- Pages.43-55
- /
- 2005
- /
- 2733-6441(pISSN)
- /
- 2733-645X(eISSN)
운동과 저출력 레이저가 말초신경손상 흰쥐의 CAMP와 조직학적 변화에 미치는 영향
The effects of Exercise and Low-Power Laser on the Changes of CMAP and Histologic factor in Peripheral Nerve Injured Rats
- 하미숙 (부산가톨릭대학 보건과학대학원 물리치료) ;
-
백일훈
(부산가톨릭대학 보건과학대학원 물리치료) ;
- 이현옥 (부산가톨릭대학교 물리치료학과) ;
- 김선엽 (부산가톨릭대학교 물리치료학과) ;
- 노민희 (부산가톨릭대학교 물리치료학과)
- Ha, Mi-Sook (Physical Therapy Major, Graduate School of Health Science, Catholic University of Pusan) ;
-
Baek, Il-Hun
(Physical Therapy Major, Graduate School of Health Science, Catholic University of Pusan) ;
- Lee, Hyun-Ok (Department of Physical Therapy, Catholic University of Pusan) ;
- Kim, Sun-Yueb (Department of Physical Therapy, Catholic University of Pusan) ;
- Rho, Min-Hee (Department of Physical Therapy, Catholic University of Pusan)
- 발행 : 2005.12.31
초록
This study was performed to investigate the effects of low-power Helium Neon Infra Red(He-Ne IR)laser irradiation and exercise on the regeneration of experimentally cut sciatic nerve in rats. The thrity Sprague-Dawley adult mail rats were assigned to the 6 groups : normal group(1), injured control groups(2), experimental groups(3). There was made artificial injured in the sciatic nerve of rats the each experimental laser group and exercise group were treated from 3 days after being injured for the 5 minutes(laser group), 10 minutes(exercise group), and 15 minutes(exercise and laser group) everyday during 2 weeks. There were measured the changes of amplitude of compound muscle action potential and histological change by the light microscopy on the sciatic nerve injured rats. The results obtained as follows : 1. In the control groups, the regeneration were slowly and slightlly progressed to compared with the experimental groups. Inflammation were much more observed, and fibrous adhesion was also observed around the sutured region of the cut sciatic nerve. 2. The amplitude of compound muscle action potential in the experimental groups were significantly increased to the injured control groups at 1 week(p<.05). The compound muscle action potential of the exercise and lased group was significantly decreased to be similar to normal group at 2 weeks(p<.05). 3. In histologic finding, in the experimental groups were observed the proliferation of the schwann cells, the infiltration of inflammatory cells and the extent of destruction at adjacent tissue were remarkably decreased on the 2 weeks. From these experimental results, it may be suggested that the laser and exercise were effected the heeling process of peripheral nerve injuried rats.