Radiation Oncology Journal

  • 제23권3호
  • /
  • Pages.194-200
  • /
  • 2005
  • /
  • 2234-1900(pISSN)
  • /
  • 2234-3156(eISSN)
대한방사선종양학회 (The Korean Society for Radiation Oncology)
권호 표지

사기질모세포 암종에서 수술 후 방사선치료의 역할: 증례보고

The Role of Postoperative Radiotherapy for Ameloblastic Carcinoma of the Mandible: Case Report

  • 김원택 (부산대학교 의과대학 방사선종양학교실) ;
  • 정인교 (부산대학교 의과대학 구강악안면외과학교실) ;
  • 기용간 (부산대학교 의과대학 방사선종양학교실) ;
  • 남지호 (부산대학교 의과대학 방사선종양학교실) ;
  • 권병현 (부산대학교 의과대학 방사선종양학교실) ;
  • 김동원 (부산대학교 의과대학 방사선종양학교실)
  • Kim Won Taek (Departments of Radiation Oncology, College of Medicine, Pusan National University) ;
  • Chung In Kyo (Departments oi Oral and Maxillofacial Surgery, College of Medicine, Pusan National University) ;
  • Ki Yong Kan (Departments of Radiation Oncology, College of Medicine, Pusan National University) ;
  • Nam Ji Ho (Departments of Radiation Oncology, College of Medicine, Pusan National University) ;
  • Gwon Byung Hyun (Departments of Radiation Oncology, College of Medicine, Pusan National University) ;
  • Kim Dong Won (Departments of Radiation Oncology, College of Medicine, Pusan National University)
  • 발행 : 2005.09.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

사기질모세포 암종은 악골에 발생하는 치원성 악성 종양으로 매우 드물게 보고되고 있다. 양성질환의 임상양상을 보이기도 하지만 악골 및 주변조직을 침범해 궤양 형태를 보일 수 있으므로 보통은 조직검사를 통해서 진단이 내려진다. 이런 이유로 수술 절제가 충분치 못할 수 있어 국소재발이나 원격전이의 위험에 노출되게 되므로, 수술 후의 보조적 치료 또는 재절제가 중요하다고 할 수 있다. 저자들은, 하악에서 발생한 사기질모세포 암종의 환자에서 일차 수술 후 충분한 절제연을 얻지 못해 재발한 부위에 대해 재수술 후 재발 위험부위에 대한 보조적 방사선치료를 시행한 증례를 토대로, 최근의 문헌고찰을 통해 사기질모세포 암종 환자에서의 수술 후 방사선치료의 역할에 대해서 의견을 제시해 보고자 한다.

An ameloblastic carcinoma is a very rare odontogenic malignant tumor, which sometimes have a benign clinical nature, but typically have aggressive features, with large ulcerative lesion and extensive local destruction. These clinical characteristics make the complete surgical removal of a tumor difficult. As a consequence, a poor prognosis may result due to local recurrence and distant metastasis. For this reason, it is important to consider adjuvant therapies for high-risk ameloblastic carcinoma patients. Here, the case of a recurrent ameloblastic carcinoma that occurred in the mandible after primary surgery is reported. The lesion was treated with further local excision, followed by postoperative radiotherapy. Also, a few remarks on the role of postoperative radiotherapy in patient with ameloblastic carcinoma have been made from a review of the current literatures on the treatment of this type of lesion.

키워드

참고문헌

  1. Goldenberg D, Sciubba L. Koch W, Tufano RP. Malignant odontogenic tumors: a 22-year experience. Laryngoscope 2004;114:1770-1774 https://doi.org/10.1097/00005537-200410000-00018
  2. Slootweg PJ, Muller H. Malignant ameloblatoma or ameloblastic carcinoma. Oral Surg 1984;57:168-176 https://doi.org/10.1016/0030-4220(84)90207-X
  3. Gardner DG. Some current concepts on the pathology of ameloblastomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996;82:660-669 https://doi.org/10.1016/S1079-2104(96)80441-0
  4. Elzav RP. Primary intraosseous carcinoma of the jaws review and update of odontogenic carcinomas. Oral Surg Ora Med Oral Pathol 1982;54:299-303 https://doi.org/10.1016/0030-4220(82)90099-8
  5. Simoko EJ, Brannon RB, Eibling DE. Ameloblastic carcinoma of the mandible. Head Neck 1998;20:654-659 https://doi.org/10.1002/(SICI)1097-0347(199810)20:7<654::AID-HED14>3.0.CO;2-4
  6. Corio RL. Goldblatt LI. Edwards PI, Hartment KS. Ameloblastic carcinoma: a clinicopathologic study and assessment of eight cases. Oral Surg Oral Med Oral Pathol 1987;64: 570-576 https://doi.org/10.1016/0030-4220(87)90063-6
  7. Bruce RA. Jackson IT. Ameloblastic carcinoma: report of an aggressive case and review of the literature. J Craniomaxillofac Surg 1991;19:267-271 https://doi.org/10.1016/S1010-5182(05)80068-X
  8. Datta R. Winston JS. Diaz-Reyes G. et al. Ameloblastic carcinoma: report of an aggressive case with multiple bony metastases. Am J Otolaryngol 2003;24:64-69 https://doi.org/10.1053/ajot.2003.15
  9. Dorner L. Sear AJ. Smith GT. A case of ameloblastic carcinoma with pulmonary metastases, Br J Oral Maxillofac Surg 1988;26:503-510 https://doi.org/10.1016/0266-4356(88)90073-3
  10. Kim KM. Hwang EH. Cho JO. Lee SR. Ameloblastic carcinoma of the mandible. Korean J Oral Maxillofac Radiol 2001; 31:109-115
  11. Sastre J. Munoz M. Naval L. Adrados M. Ameloblastic carcinoma of the maxilla: report of a case. J Oral Maxillofac Surg 2002;60: 102-104 https://doi.org/10.1053/joms.2002.29086
  12. Cizmecy O. Asian A. Onel D. Demiryont M. Ameloblastic carcinoma ex ameloblastoma of the mandible: Case report. Otolaryngol Head Neck Surg 2004;130:633-634 https://doi.org/10.1016/j.otohns.2003.11.012
  13. Eliasson AH. Moser RJ. Tenholder MF. Diagnosis and treatment of metastatic ameloblastoma. South Med J 1989;82: 1165-1168 https://doi.org/10.1097/00007611-198909000-00027
  14. Atkinson CH. Harwood AR. Cummings BJ. Ameloblastoma of the jaw: A reappraisal of the role of megavoltage irradiation. Cancer 1984;53:869-873 https://doi.org/10.1002/1097-0142(19840215)53:4<869::AID-CNCR2820530409>3.0.CO;2-V
  15. Dhir K. Sciubba J. Tufano RP. Ameloblastic carcinoma of the maxilla. Oral Oncol 2003;39:736-741 https://doi.org/10.1016/S1368-8375(03)00036-8
  16. Ramadas K. Jose C. Subhashini J. et al. Pulmonary metastasis from ameloblastoma of the mandible treated with cisplatin, acriarnycin and cyclophosphamide. Cancer 1990;66: 1475 https://doi.org/10.1002/1097-0142(19901001)66:7<1475::AID-CNCR2820660707>3.0.CO;2-D