Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

11-Methoxyviburtinal, A New Iridoid from Valeriana jatamansi

  • Chen Ye-Gao (Department of Chemistry, Hainan Normal University, Department of Chemistry, Yunnan Normal University) ;
  • Yu Li-Li (Department of Chemistry, Yunnan Normal University) ;
  • Huang Rong (Experimental Center, Yunnan University) ;
  • Lv Yu-Ping (Department of Chemistry, Yunnan Normal University) ;
  • Gui Shi-Hong (Department of Chemistry, Yunnan Normal University)
  • Published : 2005.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

Five compounds of iridoids, lignan and phenylpropanoid glycosides were isolated from the roots of Valeriana jatamansi by column chromatography. Their structures were elucidated as 11-methoxyviburtinal (1), baldrinal (2), prinsepiol-4-O-${\beta}$-D-glucoside (3), coniferin (4), and hexacosanic acid (5) by spectroscopic analysis. 11-Methoxyviburtinal was a new compound, and others were isolated from the plant for the first time.

Keywords

References

  1. Bach, K. K., Ghia, F., and Torssell, K. B. G., Valtrates and lignans in Valeriana microphylla. Planta Med., 59, 478-479 (1993) https://doi.org/10.1055/s-2006-959740
  2. Bounthanh, C., Bergmann, C., Beck, J. P., Haag-Berrurier, M., and Anton, R., Valepotriates, a new class of cytotoxic and antitumor agents. Planta Med., 41, 21-28 (1981) https://doi.org/10.1055/s-2007-971668
  3. Greca, M. D., Ferrara, M., Fiorentino, A., Monaco, P., and Previtera, L., Antialgal compounds from Zantedeschia aethiopica. Phytochemistry, 49, 1299-1304 (1998) https://doi.org/10.1016/S0031-9422(98)00092-2
  4. Houghton, P. J., The biological activity of valerian and related plants. J. Ethnopharmacol., 22, 121-142 (1988) https://doi.org/10.1016/0378-8741(88)90123-7
  5. Matsumura, T., Ishikawa, T., and Kitajima, J., Water-soluble constituents of caraway: aromatic compound, aromatic compound glucoside and glucides. Phytochemistry, 61, 455-459 (2002) https://doi.org/10.1016/S0031-9422(02)00288-1
  6. Mikhova, B. P., Handjieva, N. V., Popov, S. S., and Spassov, S. L., Structural investigation of valepotriates on the basis of Hlanthanide-induced shifts. J. Nat. Prod., 50, 1141-1145 (1987) https://doi.org/10.1021/np50054a023
  7. Ming, D. S., Yu, D. Q., Yang, Y. Y., and He, C. H., The structures of three novel sesquiterpenoids from Valeriana jatamansi Jones. Tetrahedron Lett., 38, 5205-5208 (1997) https://doi.org/10.1016/S0040-4039(97)01112-X
  8. Piccinelli, A. L., Arana, S., Caceres, A., Bianca, R. E. V., Sorrentino, R., and Rastrelli, L., New Lignans from the roots of Valeriana prionophylla with antioxidative and vasorelaxant activities. J. Nat. Prod., 67, 1135-1140 (2004) https://doi.org/10.1021/np049879c
  9. Tang, Y. P., Liu, X., and Yu, B., Two new flavone glycosides from Valeriana jatamansi. J. Asian Nat. Prod. Res., 5, 257-261 (2003) https://doi.org/10.1080/1028602031000105867
  10. Tang, Y. P., Liu, X., and Yu, B., Iridoids from the rhizomes and roots of Valeriana jatamansi. J. Nat. Prod., 65, 1949-1952 (2002) https://doi.org/10.1021/np0203335
  11. Thies, P. W., Finner, E., and David, S., Ober die wirkstoffe des baldrians. Planta Med., 41, 15-20 (1981) https://doi.org/10.1055/s-2007-971667
  12. Thies. P. W., Die konstitution der valepotriate mitteilung uber die wirkstoffe des baldrians. Tetrahedron, 24, 313-347 (1968) https://doi.org/10.1016/0040-4020(68)89032-5
  13. Wang, Z. Y., and Niu, F. D., Studies on the chemical constituents of the essential oil of Valeriana jatamansi Jones. Acta Botanica Yunnanica, 2, 58-61 (1980)
  14. Zhang, R. W., Wu, H. X., and Li, Q. H., The isolation and identification of iridoids from Valeriana jatamansi. Acta Botanica Yunnanica, 8, 107-108 (1986)