KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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CSP [Chiral Stationary phase] for SMB Chromatography

SMB 크로마토그래피에서 키랄정지상 [Chiral Stationary Phase, CSP]의 사용

  • Kim Byung-Lip (Department of Chemical Engineering, Chungnam National University) ;
  • Kim In-Ho (Department of Chemical Engineering, Chungnam National University)
  • Published : 2005.06.01
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Abstract

Simulated moving bed (SMB) chromatography was used in the petrochemical industry in the 1960s and its use has been widened to separate chiral compounds in the 1990s. Chiral stationary phase (CSP) is the key component in SMB for the separation of the chiral compounds. CSP has been developed for the analytical use in HPLC, however, its development successfully adapted for the preparative use in SMB chromatography. This review covers the present state-art technology of CSP for SMB chromatography in terms of selectivity, stability, and capacity.

Keywords

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