Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
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A CLINICAL STUDY OF ANESTHETIC EFFICACY OF ALKALINIZING LIDOCAINE IN INFERIOR ALVEOLAR NERVE BLOCKS

하치조신경 전달 마취 시 알칼리화 된 리도카인의 마취 효능에 관한 임상적 연구

  • Kim, Tae-Hwan (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Dankook University) ;
  • Kim, Kyung-Wook (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Dankook University) ;
  • Kim, Chul-Hwan (Dept. of Oral & Maxillofacial Surgery, School of Dentistry, Dankook University)
  • 김태환 (단국대학교 치과대학 구강악안면외과학교실) ;
  • 김경욱 (단국대학교 치과대학 구강악안면외과학교실) ;
  • 김철환 (단국대학교 치과대학 구강악안면외과학교실)
  • Published : 2005.05.31
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Abstract

Inferior alveolar nerve block using lidocaine is the most frequent local anesthetic method in the dental treatment, but clinically it is not always successful. The 2% lidocaine cartridge has been used commonly in dental anesthesia. It contains vasoconstrictor and antioxidant, which presents low pH which provides chemical stability and longer shelf life. But alkalinized local anesthetics has less tissue trauma, easier dissociation of the non-ionized base which penetrates nerve sheath, rapid onset and more intensity. In this study, in inferior alveolar nerve block, alkalinized lidocaine using sodium bicarbonate (experimental group) is compared with plain lidocaine (control group) about injection pain, anesthetic onset, duration and postinjection discomfort. In inferior alveolar nerve block, alkalinized lidocaine using sodium bicarbonate showed lower injection pain. There was significant difference statistically from plain lidocaine(p=0.019). Comparing with plain lidocaine, alkalinized lidocaine produced more rapid onset (lip & pulp anesthetic onset), there was no significant difference(p>0.05). but there was boundary significance (0.050.05). These results suggest that addition of sodium bicarbonate to 2% lidocaine(1:100,000 epinephrine) for inferior alveolar nerve block is more effective for reduction of injection pain and onset time.

Keywords

References

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