Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Anesthetic Effects of Medetomidine-Tiletamine/Zolazepam Combination in Green Iguanas (Iguana iguana)

그린 이구아나에서 Medetomidine-Tiletamine/Zolazepam의 병용마취효과

  • Jung So Young (Seoul Grand Park Zoo Veterinary Hospital Examination Affairs Division) ;
  • Kim Min-Su (Department of Veterinary Surgery, College of Veterinary Medicine, Seoul National University) ;
  • Kim Sun Young (Department of Veterinary Surgery, College of Veterinary Medicine, Seoul National University) ;
  • Seo Kang-Moon (Department of Veterinary Surgery, College of Veterinary Medicine, Seoul National University) ;
  • Nam Tchi-Chou (Department of Veterinary Surgery, College of Veterinary Medicine, Seoul National University)
  • Published : 2005.09.01
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Abstract

This study was performed to investigate the anesthetic effects of intramuscularly administered medetomidinetiletamine/zolazepam ($Zoletil^{(R)}$) in the green iguana. The doses of medetomidine were 50, 100 and 150 ${\mu}g/kg$ in each groups and tiletamine/zolazepam was administered at doses of 10 mg/kg in all groups. Heart rate, respiratory rate and body temperature were measured. Anesthetic depth was evaluated by righting reflex. In all study groups, heart rate and respiratory rate significantly decreased at 5 minutes after anesthetic administration, and gradually increased after 30 minutes. The present study suggested that the combination of 100 ${\mu}g/kg$ of medetomidine and 10 mg/kg of tiletamine/zolazepam provided rapid, safe, and effective anesthesia for the green iguana.

그린 이구아나에서 medetomidine과 tiletamine/zolazepam의 병용마취효과를 알아보기 위하여 본 실험을 실시하였다. Medetomidine은 MZ50, MZ100 및 MZ150 군에서 각각 50, 100 및 150 ${\mu}g/kg$를 사용하였다. Tiletamine/zolazepam ($Zoletil^{(R)}$)은 모든 군에서 10 mg/kg을 적용하였다. 10마리의 건강한 이구아나 (420-490 g)를 2주 간격으로 3회 실험 하였다. 심박동수, 호습수 그리고 체온을 측정하였으며 righting reflex를 통해 마취 심도를 평가하였다. 모든 군에서 심박동수와 호흡수는 마취주사 5분 후에 유의성 있는 감소를 보였으며 (P<0.05) 30분 후에는 지속적으로 증가하는 양상을 보였다. 본 연구결과 medetomidine 100 ${\mu}g/kg$과 tiletamine/zolazepam 10 mg/kg의 병용이 그린이구아나에서 빠르고 안정적이며 효과적인 마취를 제공한다고 생각된다.

Keywords

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