폐와 하악골에 다발성으로 발생한 Histiocytosis X

MULTIPLE LANGERHANS CELL HISTIOCYTOSIS AT THE LUNG AND MANDIBLE: CASE REPORT

  • 황진혁 (서울아산병원 구강악안면외과학교실) ;
  • 이부규 (서울아산병원 구강악안면외과학교실)
  • Hwang, Jin-Hyuk (Department of Oral & Maxillofacial Surgery, Asan Medical Center) ;
  • Lee, Bu-Kyu (Department of Oral & Maxillofacial Surgery, Asan Medical Center)
  • 발행 : 2005.06.30

초록

Hitiocytosis X, recently termed Langergans cell histiocytosis, is a rare disease histologically characterized by an abnormal proliferation of histiocytes, and of which the pathophysiology is still ambiguous. The clinical presentation is highly varied. Typically, there is a solitary or multiple bony involvements, and less frequently, lesions are found in other organs such as the lungs, liver, lymph nodes, skin, and mucosae. Interestingly, so far, there has been no report which shows multiple developments in both soft and hard tissues. In this report, we present a case of hitiocytosis X in both mandible and lung. This may provide some information for understanding the pathophysilogy of the histiocytosis X.

키워드

참고문헌

  1. Broadbent V, Egeler RM, Nesbit ME Jr: Langergans'cell histiocytosis- clinical and epidermiological aspects. Br J Cancer 1994;23:11-16
  2. Nezelof C, Frileux-Herbet F, Cronier-Sachat J: Disseminated histiocytosis X. Cancer 1979;44:1824-1838 https://doi.org/10.1002/1097-0142(197911)44:5<1824::AID-CNCR2820440542>3.0.CO;2-J
  3. Lichtenstein L: Histiocytosis; integration of eosinophilic granuloma of bone,'Letterer-Siwe disease', and 'Schuller-Christian disease' as related manifestations of a single nosologic entity. Arch Pathol 1953;56:84-102
  4. Bottomley WK, Gabriel SA, Corio RL, Jacobson RJ, Rothchild N. Histiocytosis X: report of an oral soft tissue lesion without bony involvement. Oral Surg Med Oral Pathol 1987;63:228-231 https://doi.org/10.1016/0030-4220(87)90318-5
  5. Pringle GA, Daley TD, Veinot LA, Wysocki GP: Langerhans'cell histiocytosis in association with periapical granulomas and cysts. Oral Surg Oral Med Oral Pathol 1992;74:186-192 https://doi.org/10.1016/0030-4220(92)90381-Y
  6. McClain K, Weiss RA: Viruses and Langerhans cell histiocytosis: Is there a link? Br J Cancer 1994;23:s34-36
  7. Ardekian L, Peled M. Rosen D, et al.: Clinical and radiographic features of eosinophilic granuloma in the jaws. Review of 41 lesions treated by surgery and low-dose radiotherapy. Oral Surg Oral Med Oral Pathol Oral Rdiol Endod 1999;87:238
  8. Roychoudhury A, Shah N. Parkash H, et al: Eosinophilic granuloma of the jaws. Br J Oral Maxillofac Surg 1998;36:380 https://doi.org/10.1016/S0266-4356(98)90651-9
  9. McGavran MH, Spady HA: Eosinophilic granuloma of bone. A study of twenty-eight cases. J Bone Joint Surg 1960;42:979
  10. Womer RB, Raney RB, D'Angio GJ: Healing rates of treated und untreated histiocytosis X. Pediatrics 1985;76:286
  11. Broadbent V. Davices EG, Heaf D, et al: Spontaneous remission of multi-system histiocytosis X. Lancet I: 253, 1984
  12. Jaffe HL, Lichtenstein L: Eosinophilic granuloma of bone. A condition affecting one, several, or many bones, but apparently limited to the skeleton, and representing the mildest clinical expression of peculiar inflammatory histiocytosis also underlying Lettere-Siwe disease and Schuller-Christian disease. Arch Pathol 1944;37:99-118
  13. Milian A, Bagan JV, Basterra J, Jimenez Y, Lloria E: Histiocitosis X oral con severa destruccion del maxilar superior, Acta Otorrinolaringol Esp 1996;47:475-478
  14. Kevin G. Kempers, Lawrence M. Levin, Jeffery C.B. Stewart: Surgical Management of Langerhans'cell Histiocytosis 430
  15. Wassmend M, Anders He: Uber eine bisher unbekannte detruierende Erkrankung der Kieferknochen (About an innominated destruction dieases of the jaw). Viertelijahrsschrift fur Zahnheilkunde 1932;48: 157-206
  16. Schroff J: Eosinophilic granuloma of bone. Oral Surg Oral Med Oral Pathol 1948;1:1256-64
  17. Mellor WC, Stockdale CR: Eosinophilic granuloma: report of three cases, one exhibiting mucosal lesions. Oral Surg Oral Med Oral Pathol 1958;11:1196-209 https://doi.org/10.1016/0030-4220(58)90271-8
  18. Raney RB, D'Anglio GJ: Langerhans' cell histiocytosis (histiocytosis X): Experience at the Children's Hospital of Philadelphia, 1970-1984. Med Pediatr Oncol 1989;17:20-28 https://doi.org/10.1002/mpo.2950170106
  19. Hartman KS: Histiocytosis X: A review of 114 cases with oral involvement. Oral Surg Oral Med Oral Pathol 1980;49:38
  20. Robert Vassallo: Pulmonary Langerhans'cell histiocytosis. Clin Chest Med 2004;561-571