Korean Journal of Oriental Medicine (한국한의학연구원논문집)
- Volume 11 Issue 2
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- Pages.97-111
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- 2005
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- 1229-3377(pISSN)
The Experimental Study on Anti-thrombotic and Anti-inflammatory Effect of ChungyeolHaedogHwaeoTang(CHHT)
청열해독화어탕(淸熱解毒化瘀湯)의 항혈전(抗血栓) 및 항염(抗炎)효과에 관한 실험적(實驗的) 연구(硏究)
- Kim, Sung-Ran (College of Oriental Medicine, Daejeon Univ.) ;
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Ahn, Sang-Woo
(Korea Institute of Oriental Medicine) ;
- Yoo, Dong-Yeoul (Korea Institute of Oriental Medicine)
- Published : 2005.12.30
Abstract
This study was performed to evaluate anti-thrombotic activities and anti-inflammatory effects of ChungyeolHaedogHwaeoTang water extract(CHHT). The results were summarized as follows. In experiment of anti-thrombotic effect; 1. CHHT inhibited human platelet aggregation induced by ADP and epinephrine as compared with the control group, and inhibited pulmonary embolism induced by collagen and epinephrine (inhibitory rate is 37.5%). 2. CHHT increased platelet number significantly, and also CHHT shortened PT and APTT significantly as compared with the control group in thrombus model induced by dextran. In experiment of anti-inflammatory effect; 3. CHHT inhibited
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