대한예방한의학회지 (Journal of Society of Preventive Korean Medicine)
- 제9권1호
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- Pages.135-141
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- 2005
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- 1226-7066(pISSN)
고삼에서 항균물질의 분리
Isolation of Antimicrobial Active Substances from Sophorae Radix
- 김윤경 (원광대학교 약학대학 한약학과) ;
- 한완수 (목원대학교 테크노과학대학 생의약화장품학부) ;
- 정승일 (목원대학교 테크노과학대학 생의약화장품학부) ;
- 이기남 (원광대학교 한의학전문대학원 제3의학과) ;
- 김현주 (원광대학교 약학대학 한약학과) ;
- 이정호 (원광대학교 약학대학 한약학과)
- Kim, Yun-Gyoung (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) ;
- Han, Wan-Soo (Division of Biomedicine & Cosmetics, College of Science and Technology) ;
- Jeong, Seung-Il (Division of Biomedicine & Cosmetics, College of Science and Technology) ;
- Lee, Ki-Nam (Department of Third Medicine, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
- Kim, Hyun-Ju (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) ;
- Lee, Jeong-Ho (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University)
- 발행 : 2005.06.29
초록
Bioassay-directed fractionation of the dired roots of Sophorae Radix led to the isolation of Sophoraflavanone G. Their structures were elucidated using 1H-NMR, 13C-NMR, UV, IR and mass spectral ananlyses. These compounds exhibited a moderate antimicrobial activities against Streptococcus gordonii, Actinobacillus actinomycetemoomitans and Porphylomonas gingivalis.