References
- Thompson, C.B. Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462, 1995.
- Zornig, M., Hueber, A., Baum, W., Evan, G.. Apoptosis regulators and their role in tumorigenesis: Biochim Biophys Acta 1551, Fl-F37, 2001.
- Matsuzawa, A.,Ichijo, H. Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1: J Biochem (Tokyo) 130, 1-8, 2001.
- Jacobson, M.D., Weil, M., Raff, M.C. Programmed cell death in animal development: Cell 88, 347-354, 1997.
- Kaufmann, S.H., Earnshaw, W.C. Induction of apoptosis by cancer chemotherapy: Exp Cell Res 256, 42-49, 2000.
- Bamford, M., Walkinshaw, G., Brown, R. Therapeutic applications of apoptosis research: Exp Cell Res 256, 1-11, 2000.
- Onishi, Y., Azurna, Y., Sato, Y., Mizuno, Y., Tadakurna. T., Kizaki, H. Topoisomerase inhibitors induce apoptosis in thymocytes: Biochim Biophys Acta 1175, 147-54, 1993.
- Bertrand, R., Solary, E., Jenkins, J., Pommier, Y. Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors: Exp Cell Res 207, 388-397, 1993.
- Evans, D.L.,Dive, C. Effects of cisplatin on the induction of apoptosis in proliferating hepatoma cells and nonproliferating immature thymocytes: Cancer Res 53, 2133-2139 1993.
- Friesen, C. Herr, I., Krammer, P.H.,Debatin, K.M. Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 2, 574-577, 1996.
- Bacus, S. S., Gudkov, A.V., Lowe, M., Lyass, J., Yung, Y., Komarov, A.P., Keyomarsi. K, Yarden, Y., Seger, R. Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53:Oncogene 20, 147-155, 2001.
- Xia, Z., Dickens, M., Raingeaud, L Davis, R.J., Greenberg, M.E. Opposing effects of ERK and JNK-p38 MAP kinascs on apoptosis: Science 270, 1326-1331, 1995.
- Sankawa, U., Ebizuka, Y., Miyazaki, T., Isomura, Y., Otsuka, H. Antitumor activity of shikonin and its derivatives:Chem Pharm Bull (Tokyo) 25, 2392-2395, 1977.
- Ozaki, Y., Ohno, A, Saito, Y.,Satake, M. Accelerative effect of shikonin, alkannin and acetylshikonin on the proliferation of granulation tissue in rats: Biol Pharm Bull 17, 1075-1077, 1994.
- Tanaka, S., Tajima, M., Tsukada, M.,Tabata, M. A comparative study on anti-inflammatory activities of the enantiomers, shikonin and alkannin: J Nat Prod 49, 466-469, 1986.
- Tanaka, Y., Odani, T. Pharmacodynamic study on 'Shiunko.' I. Antibacterial effect of 'Shiunko':Yakugaku Zasshi 92, 525-530, 1972.
- Yoon, Y., Kim, Y.O., Lim, N.Y., leon, W.K.,Sung, H.J. Shikonin, an ingredient of Lithospermum erythrorhizon induced apoptosis in HL60 human premyelocytic leukemia cell line: Planta Med 65, 532-535, 1999.
- Gao, D., Hiromura, M., Yasui, H.,Sakurai, H. Direct reaction between shikonin and thiols induces apoptosis in HL60 cells:Biol Pharm Bull 25, 827-832, 2002.
- Ahn, B.Z., Baik, K.U., Kweon, G..R., Lim, K, Hwang, B.D. Acylshikonin analogues: synthesis and inhibition of DNA topoisomerase-I: J Med Chem 38, 1044-1047, 1995.
- Fujii, N., Yamashita, Y., Arima, Y., Nagashima, M.,Nakano, H. Induction of topoisomerase II-mediated DNA cleavage by the plant naphthoquinones plumbagin and shikonin: Antimicrob Agents Chemother 36, 2589-2594, 1992.
- Hashimoto, S., Xu, M., Masuda, Y., Aiuchi, T., Nakajo, S., Cao, J., Miyakoshi, M., Ida, Y., Nakaya, K beta-hydroxyisovalerylshikonin inhibits the cell growth of various cancer cell lines and induces apoptosis in leukemia HL-60 cells through a mechanism different from those of Fas and etoposide: J Biochem (Tokyo) 125, 17-23, 1999.
- Singh, E. Gao, D., Lebwohl, M.G.,Wei, H. Shikonin modulates cell proliferation by inhibiting epidermal growth factor receptor signaling in human epidermoid carcinoma cells:. Cancer Lett 200, 115-121, 2003.
- Guo, X.P., Zhang, X.Y.,Zhang, S.D. Clinical trial on the effects of shikonin mixture on later stage lung cancer: Zhong Xi Yi Jie He Za Zhi 11, 598-599, 580, 1991.
- Song, G..Y., Kim, Y, You, Y.J., Cho, H.,Ahn, B.Z. Naphthazarin derivatives (VII): antitumor action against ICR mice bearing ascitic 5-180 cells: Arch Pharm Res 24, 35-38, 2001.
- Ishiyama, M., Tominaga, H., Shiga, M., Sasamoto, K, Ohkura, Y., Ueno, K A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet: Biol Pharm Bull 19, 1518-1520, 1996.
- Nicholson, D.W. From bench to clinic with apoptosis-based therapeutic agents: Nature 407, 810-816, 2000.
- Oltvai, Z.N., Milliman, C.L.,Korsmeyer, S.J. &1-2 beterodirrerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death: Cell 74, 609-619, 1993.
- Zhu, X.F., Liu, Z.C.,; Xie, B.F., Li, Z.M., Feng, G.K, Xie, H.H., Wu, S.J. Yang, R.Z. Wei, X.Y., Zeng, Y.X, Involvement of caspase-3 activation in squamocin-induced apoptosis in leukemia cell line HL-60: Life Sci 70, 1259-1269, 2002.
- Lewis, T.S., Shapiro, P.S., Ahn, N.G. Signal transduction through MAP kinase cascades: Adv Cancer Res 74, 49-139, 1998.
- Chuang, S,M. Wang, I.C., Yang, J.L. Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium: Carcinogenesis 21, 1423-1432, 2000.