Bulletin of the Korean Chemical Society

  • 제26권5호
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  • Pages.763-768
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  • 2005
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  • 0253-2964(pISSN)
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  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Construction of an Improved Tandem Time-of-flight Mass Spectrometer for Photodissociation of Ions Generated by Matrix-assisted Laser Desorption Ionization (MALDI)

  • Moon, Jeong-Hee (National Creative Research Initiative Center for Control of Reaction Dynamics and School of Chemistry, Seoul National University) ;
  • Yoon, So-Hee (National Creative Research Initiative Center for Control of Reaction Dynamics and School of Chemistry, Seoul National University) ;
  • Kim, Myung-Soo (National Creative Research Initiative Center for Control of Reaction Dynamics and School of Chemistry, Seoul National University)
  • 발행 : 2005.05.20
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초록

An improved tandem time-of-flight (TOF) mass spectrometer for the photodissociation (PD) study of ions generated by matrix-assisted laser desorption ionization (MALDI), MALDI-TOF-PD-TOF, has been designed and constructed. Recording a full spectrum with better than unit mass resolution even in low mass range has been achieved without reflectron voltage stepping which was needed in the previous version. Other aspects of the improvement, such as those in the data system which now allow 10-100 times faster spectral acquisition than with the previous instrument, are described. Rationale for the ideas which have led to the improvements is presented also.

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참고문헌

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피인용 문헌

  1. Characteristics of photodissociation at 193 nm of singly protonated peptides generated by matrix-assisted laser desorption ionization (MALDI) vol.17, pp.12, 2006, https://doi.org/10.1016/j.jasms.2006.07.021
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  3. Time-resolved photodissociation study of singly protonated peptides with a histidine residue generated by matrix-assisted laser desorption ionization: Dissociation rate constant and internal temperature vol.20, pp.8, 2009, https://doi.org/10.1016/j.jasms.2009.04.008
  4. Observation of phosphorylation site-specific dissociation of singly protonated phosphopeptides vol.21, pp.1, 2010, https://doi.org/10.1016/j.jasms.2009.09.003
  5. Dissociation kinetics of singly protonated leucine enkephalin investigated by time-resolved photodissociation tandem mass spectrometry vol.21, pp.7, 2010, https://doi.org/10.1016/j.jasms.2010.03.025
  6. Expansion Cooling in the Matrix Plume is Under-Recognized in MALDI Mass Spectrometry vol.22, pp.6, 2011, https://doi.org/10.1007/s13361-011-0115-y
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  11. Resolution of infrared matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using glycerol; enhancement with a disperse laser beam vol.21, pp.8, 2007, https://doi.org/10.1002/rcm.2983
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