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Antithrombosis and Antioxidant Activity of Methanol Extract from Different Brands of Rice

시판 쌀 메탄을 추출물의 항혈전 및 항산화 활성

  • Sohn, Ho-Yong (Dept. of Food and Nutrition, Andong National University) ;
  • Kwon, Chong-Suk (Dept. of Food and Nutrition, Andong National University) ;
  • Son, Kun-Ho (Dept. of Food and Nutrition, Andong National University) ;
  • Kwon, Gi-Seok (The School of Bioresource Sciences, Andong National University) ;
  • Kwon, Yun-Suk (Dept. of Food and Nutrition, Andong National University) ;
  • Ryu, Hee-Young (Dept. of Food and Nutrition, Andong National University) ;
  • Kum, Eun-Joo (Dept. of Food and Nutrition, Andong National University)
  • 손호용 (안동대학교 식품영양학과) ;
  • 권정숙 (안동대학교 식품영양학과) ;
  • 손건호 (안동대학교 식품영양학과) ;
  • 권기석 (안동대학교 생명자원과학부) ;
  • 권윤숙 (안동대학교 식품영양학과) ;
  • 류희영 (안동대학교 식품영양학과) ;
  • 금은주 (안동대학교 식품영양학과)
  • Published : 2005.06.01

Abstract

Antithrombosis and antioxidant activity of the methanol extracts, which were prepared from 51 different brands of rice, were evaluated to investigate bioactive-substances. Among them, the extract of sample No. 2, 25, 40 and 41 showed strong thrombin inhibition activities ($401\~764\%$ inhibition at 5 mg/mL), and the extract of sample No. 5, 9, 23, 36, 44 and 48 showed strong DPPH scavenging activities ($40.8\~64.1\%$ at 0.4 mg/mL), respectively. The average contents of total flavonoid and polyphenol with 50 brands of rice were 51.89 mg/kg and 195.23 mg/kg, respectively. However, the activities were not linked with the contents of flavonoid and polyphenol. By the treatment at $100^{\circ}C$ for 10 min, the activities of the selected rices were severely decreased. Maximal remaining activities of antithrombosis and antioxidant were $208\%$ of No. 40 and $23.2\%$ of No. 48, respectively. These results support a functional superiority of rice-based livelihood, and suggest that the development of healthy food using functional ingredients of rice is possible.

일반 쌀의 유용 생리활성 성분에 대한 연구의 일환으로 국내 시판되는 51종의 다양한 브랜드 쌀의 메탄을 추출물을 조제하여 항혈전 활성과 항산화 활성을 검토하였다. 그 결과 4종의 시판 쌀 추출물이 5 mg/mL의 농도에서 $401\~764\%$의 우수한 항혈전 활성을 나타내었으며, 6종의 쌀 추출물은 0.4 mg/mL의 농도에서 $40.8\~64.12\%$의 자유래디컬 소거능을 나타내어 우수한 항산화 능력을 확인하였다. 현미쌀눈을 제외한 50종의 평균 flavonoid 함량은 51.89 mg/kg, 평균 polyphenol 함량은 195.23 mg/kg이었으며, 이는 항혈전, 항산화 활성과 직접적인 상관관계는 나타나지 않았다. 유용성분의 효율적인 이용 및 식품가공 적성 검토를 위해 항혈전 및 항산화 활성성분의 열안정성을 검토한 결과, $100^{\circ}C$, 10분간 가열처리에 의해 모두 급격한 활성감소가 나타났으나, 시료 40번의 경우, $208\%$의 항혈전 활성을, 시료48번의 경우 $23.2\%$의 자유래디컬 소거능을 유지하였다. 이러한 결과는 쌀 중심 식생활의 영양적, 기능적 우수성을 의미하며, 쌀의 식품가공기술의 개발과 함께 다양한 비열처리 식품으로의 개발이 필요함을 제시한다. 또한 본 결과는 쌀의 유용성분을 이용하는 혈행 개선 및 항산화 건강식품의 개발이 가능함을 제시하고 있다.

Keywords

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