Environmental Mutagens and Carcinogens (한국환경성돌연변이발암원학회지)
- Volume 25 Issue 1
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- Pages.1-5
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- 2005
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- 1225-6307(pISSN)
Antimetastatic Effects of Capsaicin in Murine B16 Melanoma Cell Lines
- Hwang Myung Sil (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Yum Young Na (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Kang Ho Il (National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Kim Ok Hee (National Institute of Toxicological Research, Korea Food and Drug Administration)
- Published : 2005.03.01
Abstract
The present work was undertaken to evaluate the antimetastatic potential of capsaicin (8methyl-N-vanillyl-6-nonenamide) by measuring its effects on matrix metalloproteinase activity, cell invasion and lung metastasis. Significant inhibition of matrix metalloproteinase-2 activity by capsaicin (100
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