한방안이비인후피부과학회지 (The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology)
- 제17권1호
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- Pages.126-130
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- 2004
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
丹參 추출물로부터 항균물질의 분리와 항균효과
Isolation and Effect of Antimicrobial Compounds from Extracts of Salvia Miltiorrbiza Bunge
초록
Objectives; Bioassay-directed fractionation of the dried roots of Salvia miltiorrhiza led to the isolation of abietane tanshinones, crptotanshinone and dihydrotanshinone. Methods: Their structures were elucidated using 1H-and 13C-NMR, UV, IR and mass spectral analysis. Result and Conclusions : These compounds exhibited a moderate antimicrobial activities against Staphylococcus epidemidis, Staphylococcus aureus, Staphylococcus pyogene. Actinobacillus actinomycetemcomitans, Escherichia coil, Enterbacter cloacae, Pseudomonas aeruginosa, Citrobacter freundii, and Samonella typhimurium.