Korean Journal of Biological Psychiatry (생물정신의학)
- Volume 11 Issue 1
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- Pages.40-48
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- 2004
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- 1225-8709(pISSN)
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- 2005-7571(eISSN)
A Study of Visual Event-Related Potential P300 in Schizophrenia
정신분열병의 시각자극 사건유발전위 P300에 대한 연구
- Oh, Dong-Hoon (Department of Neuropsychiatry, College of Medicine, Hanyang University and Mental Health Institute) ;
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Nam, Jung-Hyun
(Department of Neuropsychiatry, College of Medicine, Hanyang University and Mental Health Institute) ;
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Ahn, Dong-Hyun
(Department of Neuropsychiatry, College of Medicine, Hanyang University and Mental Health Institute) ;
- Kim, Seok-Hyun (Department of Neuropsychiatry, College of Medicine, Hanyang University and Mental Health Institute) ;
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Choi, Joon-Ho
(Department of Neuropsychiatry, College of Medicine, Hanyang University and Mental Health Institute)
- 오동훈 (한양대학교 의과대학 신경정신과학교실 및 정신건강연구소) ;
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남정현
(한양대학교 의과대학 신경정신과학교실 및 정신건강연구소) ;
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안동현
(한양대학교 의과대학 신경정신과학교실 및 정신건강연구소) ;
- 김석현 (한양대학교 의과대학 신경정신과학교실 및 정신건강연구소) ;
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최준호
(한양대학교 의과대학 신경정신과학교실 및 정신건강연구소)
- Published : 2004.06.30
Abstract
Objective:Event-related potentials(ERPs) are electrical changes recorded at the surface of the scalp in response to stimulus presentation, and their latency and amplitude change according to cognitive processes. Through past studies of the auditory ERP in schizophrenia, the P300 has been reported to be statistically smaller and delayed in schizophrenia than comparison groups. However, studies of the visual ERP have not been systematically examined. The present study was designed to investigate the visual P300 in patients with schizophrenia and normal controls and to compare the pattern of P300 between them. Methods:The subjects were composed of patients(N=22) with schizophrenia by DSM-IV and normal controls(N=22). The visual ERPs were measured by the visual continuous performance test. P300 amplitude and latency measured on 5 scalp electrodes(Fz, Cz, Pz,