Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
권호 표지

A Case of Bilateral Diffuse Infiltration

양측 미만성 폐침윤 1예

  • Lee, Young Jae (Department of internal medicine, Kyunghee University) ;
  • Heo, Woo Young (Department of internal medicine, Kyunghee University) ;
  • Lee, Sang Wook (Department of internal medicine, Kyunghee University) ;
  • Park, Myoung Jae (Department of internal medicine, Kyunghee University) ;
  • Yoo, Jee Hong (Department of internal medicine, Kyunghee University) ;
  • Kang, Hong Mo (Department of internal medicine, Kyunghee University)
  • 이영재 (경희대학교 의과대학 내과학교실) ;
  • 허우영 (경희대학교 의과대학 내과학교실) ;
  • 이상욱 (경희대학교 의과대학 내과학교실) ;
  • 박명재 (경희대학교 의과대학 내과학교실) ;
  • 유지홍 (경희대학교 의과대학 내과학교실) ;
  • 강홍모 (경희대학교 의과대학 내과학교실)
  • Published : 20040000
Download PDF
⟨ Previous Next ⟩

Abstract

Pulmonary alveolar proteinosis is a rare disorder in which lipoproteinaceous material accumulates within the alveoli. We report a case of pulmonary alveolar proteinosis in a 41 year old female patient. She complained of a dry cough in the preceding 6 months. She presented symptoms of mild hypoxemia and diffuse infiltration at both lower lung fields. A milky fluid was obtained by bronchoalveolar lavage. We confirmed by light microscopic examinations of the lung tissues obtained by transbronchial lung biopsy. Through several follow-ups, the patients symptoms were mild.

Keywords

References

  1. Fraimow W, Cathcart RT, Taylor RC.: Physiologic and clinical aspects of pulmonary alveolar proteinosis. Ann Intern Med 1960;52:1177-94
  2. 김현태, 정희순, 한성구, 심영수, 김건열, 한용철, 박인애, 함의근: 폐포단백증 1예. 대한내과학회잡지 1987;33:668-74
  3. Rosen SH, Castleman B, Liebow AA.: Pulmonary alveolar proteinosis N Engl J Med 1958;258:1123-42
  4. Buechner HA, Ansari A.: Acute silico-proteinosis. A new pathologic variant of acute silicosis in sandblasters, characterized by histologic features resembling alveolar proteinosis. : Dis Chest 1969;55:274-8
  5. Miller RR, Churg AM, Hutcheon M, Lom S.: Pulmonary alveolar proteinosis and aluminum dust exposure. Am Rev Respir Dis 1984;130:312-5
  6. Keller CA, Frost A, Cagle PT, Abraham JL.: Pulmonary alveolar proteinosis in a painter with elevated pulmonary concentrations of titanium. Chest 1995;108:277-80
  7. McCunney RJ, Godefroi R.: Pulmonary alveolar proteinosis and cement dust: a case report. J Occup Med 1989;31:233-7
  8. Ruben FL, Talamo TS.: Secondary pulmonary alveolar proteinosis occurring in two patients with acquired immune deficiency syndrome. Am J Med 1986;80:1187-90
  9. Steer A.: Focal pulmonary alveolar proteinosis in pulmonary tuberculosis. Arch Pathol 1969;87:347-52
  10. Bhagwat AG, Wentworth P, Conen PE.: Observations on the relationship of desquamative interstitial pneumonia and pulmonary alveolar proteinosis in childhood: a pathologic and experimental study. Chest 1970;58:326-32
  11. Hallman M, Merritt TA.: Lack of GM-CSF as a cause of pulmonary alveolar proteinosis. J Clin Invest 1996;97:589-90
  12. Ramirez J.: Pulmonary alveolar proteinosis. Treatment by massive bronchopulmonary lavage. Arch Intern Med 1967;119:147-56
  13. Ramirez-R J, Schultz RB, Dutton RE.: Pulmonary alveolar proteinosis: a new technique and rationale for treatment. Arch Intern Med 1963;112:419-31
  14. 문희용, 김세규 신동환, 이기명, 장중현, 곽승민, 이홍렬, 장준, 김성규, 이원영: 폐포 단백증 치료를 위한 전폐세척술 후 발생한 뇌부종 1예. 결핵 및 호흡기 질환 1994;41:158-64
  15. Seymour JF, Presneill JJ, Schoch OD, Downie GH, Moore PE, Doyle IR, Vincent JM, Nakata K, Kitamura T, Langton D, Pain MC, Dunn AR.: Therapeutic efficacy of granulocytemacrophage colony-stimulating factor in patients with idiopathic acquired alveolar proteinosis. Am J Respir Crit Care Med 2001;163:524-31