Annals of Clinical Neurophysiology

  • 제6권1호
  • /
  • Pages.48-51
  • /
  • 2004
  • /
  • 2508-691X(pISSN)
  • /
  • 2508-6960(eISSN)
대한임상신경생리학회 (The Korean Society of Clinical Neurophysiology)
권호 표지

IgG κMonoclonal Gammopathy of Undetermined Significance와 연관된 운동신경 다발성 신경병증과 다발선 뇌신경병증

Sensorimotor Polyneuropathy and Multiple Cranial Neuropathies Associated with IgG κMonoclonal Gammopathy of Undetermined Significance

  • 전성호 (가천의과대학교 길병원 신경과학교실) ;
  • 김윤봉 (가천의과대학교 길병원 신경과학교실) ;
  • 이영배 (가천의과대학교 길병원 신경과학교실) ;
  • 박종호 (가천의과대학교 길병원 신경과학교실) ;
  • 신원철 (가천의과대학교 길병원 신경과학교실) ;
  • 박현미 (가천의과대학교 길병원 신경과학교실) ;
  • 신동진 (가천의과대학교 길병원 신경과학교실)
  • Jeon, Seong-Ho (Department of Neurology, Gachon Medical School, Gil Medical Center) ;
  • Kim, Yoon-Bong (Department of Neurology, Gachon Medical School, Gil Medical Center) ;
  • Lee, Yeong-Bae (Department of Neurology, Gachon Medical School, Gil Medical Center) ;
  • Park, Jong-Ho (Department of Neurology, Gachon Medical School, Gil Medical Center) ;
  • Shin, Won-Chul (Department of Neurology, Gachon Medical School, Gil Medical Center) ;
  • Park, Hyeon-Mi (Department of Neurology, Gachon Medical School, Gil Medical Center) ;
  • Shin, Dong-Jin (Department of Neurology, Gachon Medical School, Gil Medical Center)
  • 발행 : 2004.05.31
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초록

The occurrence of polyneuropathy in association with monoclonal gammopathy of undetermined significance (MGUS) is quite common. However, reports of MGUS associated cranial neuropathies are rare. A 63 year-old women was presented with diplopia and swallowing difficulty. Neurological examination showed limitation of abduction of right eye, right peripheral facial palsy, decreased hearing and gag reflex, left side deviation of uvula, and decreased DTR. Sensorimotor polyneuropathy were observed with elctrophysiological studies. Protein and immunoelectrophoresis revealed IgG ${\kappa}$monoclonal gammopathy. She was treated with intravenous immunoglobulin and steroid, and her symptoms and signs were improved. This case suggested that she had sensorimotor polyneuropathy and multiple cranial neuropathies associated with IgG ${\kappa}$MGUS.

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